Fitness and Nutrition for Malignant Glioma

This study is looking at how a modified Atkins diet (a low-carb eating plan) combined with a fitness program might help people with malignant glioma (a type of brain cancer). The fitness program involves supervised exercise sessions and a home exercise plan. We want to see how these interventions affect your quality of life, measured by a health questionnaire, and how many people complete the 12-week program. You may be able to join if you are 18 to 100 years old, have a confirmed diagnosis of high-grade glioma, and are generally able to care for yourself. The study plans to enroll 15 participants.

Study design
This is a pilot study, meaning it's a small-scale test, and will include 15 participants. It is an interventional study, where participants receive specific treatments.
What's involved
You would participate in a 15-week program, which includes two weekly supervised exercise sessions and an individualized home exercise program, along with following a modified Atkins diet. Your quality of life will be measured at the start and at week 12.
Compensation
Not stated in the trial record.
Follow-up
Your quality of life will be assessed at the start of the study and again at Week 12.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06665373

Fitness and Nutrition in Glioma

Active, Not Recruiting
NAAges 18+InterventionalSupportive care
NYU Langone Health
~15 participants
Updated 2026-07-01 on ClinicalTrials.gov
What's tested:Modified Atkins DietFitness Program

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in Short Form (SF)-36 Version 2 Score
Measured over Baseline, Week 12
+1 more outcome measured
Malignant Glioma
1 sites across 1 states
New York1
  • Lee Tessler, MD · PRINCIPAL_INVESTIGATOR · NYU Langone Health

This trial hasn't published a contact. View it on ClinicalTrials.gov

Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Tissue confirmed diagnosis of high-grade glioma (World Health Organization grade III or IV)
Karnofsky Performance Status (KPS) ≥ 70%
Willing to follow the study intervention and follow-up
Able to give full informed consent

Exclusion

Currently undergoing initial concurrent radiation/chemotherapy
Severe medical co-morbidities
Any medical condition which prohibits moderate to vigorous physical activity (60-85% HRmax)
Any medical condition which prohibits a restrictive diet
Neurological deficit preventing participation in moderate to vigorous physical activity
Severe psychiatric illness
  • Change in Short Form (SF)-36 Version 2 ScoreBaseline, Week 12

    The SF-36

  • Number of Participants who Complete Full 12-Week ProgramWeek 12