NCT06670651
LinkSymphoKnee (LSK) Total Knee Replacement System Study - Ultra-congruent (UC)
Enrolling by Invitation
Not specifiedAges 18–79ObservationalLinkBio Corp.
~600 participants
Updated 2025-06-10 on ClinicalTrials.gov
What's tested:total knee arthroplasty device
At a glance
Recruiting sites
0 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Knee Injury and Osteoarthritis Outcome Score - Joint Replacement (KOOS-JR) - change from baseline
Measured over 1 year postoperative
+1 more outcome measured
Conditions
Where it's being run
2 sites across 2 statesAlabama1
Illinois1
Study leadership
- Brian Schwartz, MD · PRINCIPAL_INVESTIGATOR · Illinois Bone & Joint Institute
Who to contact
This trial hasn't published a contact. View it on ClinicalTrials.gov
Do you actually qualify for this trial?
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Eligibility criteria
Inclusion
18 years or older, and skeletally mature; and
Undergoing a primary TKA for one or both knees using the cemented LinkSymphoKnee knee system as part of the surgeon's standard of care.
Able to read and understand English (because patient-reported outcome questionnaires are not validated for all potential other languages).
Exclusion
80 years of age or older,
Women who are pregnant at the time of surgery,
History of joint sepsis,
Bone defect that requires grafting,
Previous history of bone disease (e.g., severe osteoporosis or osteomalacia) which in the surgeon's opinion is severe enough to compromise device fixation,
Systemic conditions affecting bone density (e.g., inflammatory arthritis or renal disease) which in the surgeon's opinion are severe enough to compromise device fixation,
A poorly functioning contralateral total knee replacement or a contralateral revision regardless of function.
What this trial measures
- Knee Injury and Osteoarthritis Outcome Score - Joint Replacement (KOOS-JR) - change from baseline1 year postoperative
Patient-reported outcome measure (PROM) that assesses knee health based on questions about pain, stiffness, function, and daily activities. Minimum score = 0. Maximum score = 100. Higher score means a better outcome.
- Revision rate5 years postoperative
Evaluates how often patients require additional surgery to remove or replace the knee arthroplasty device components.