Biomarkers of Resiliency In Childhood Cancer Surgery

This observational study wants to understand how children and their families recover after surgery for cancer. Researchers will look at information from smartwatches worn by patients and their caregivers, answers to questionnaires, and extra blood samples. The study aims to see if these methods can measure how well patients are recovering and if there are specific patterns in their blood that are linked to stress after surgery. You may be able to join if you are 3-25 years old and have certain solid tumors, or if you are the guardian of such a patient. The study hopes to understand recovery at one year after surgery.

Study design
This is an observational study with a planned enrollment of 40 participants. It is not specified if it is randomized or blinded.
What's involved
You would wear a smartwatch for one year, complete questionnaires at several time points, and allow extra blood to be drawn during your regular care. Clinical data will also be collected.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for one year after surgery to measure surgical resilience.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06674811

Biomarkers of Resiliency In Childhood Cancer Surgery

Recruiting
Not specifiedAges 3–25Observational
Mayo Clinic
~40 participants
Updated 2026-09-14 on ClinicalTrials.gov
What's tested:Wearing SmartwatchPatient Report OutcomesBlood DrawClinical Data Review

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Surgical resilience
Measured over 1 year
Pediatric Cancer
Neuroblastoma
Sarcoma
Wilms Tumor and Other Childhood Kidney Tumors
Childhood Soft Tissue Sarcoma
Childhood Bone Sarcoma
Childhood Malignant Intestinal Neoplasm
Childhood Malignant Liver Neoplasm
Childhood Malignant Lung Neoplasm
Childhood Malignant Ovarian Neoplasm
Childhood Malignant Pleural Neoplasm
Childhood Neuroblastic Tumor
Childhood Sarcoma

NCT06674811

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Mayo Clinic

    Rochester, Minnesotastudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Stephanie Polites, M.D., M.P.H. · PRINCIPAL_INVESTIGATOR · Mayo Clinic
Mayo Clinic Pediatric Surgery Clinical Research Unit
Email the study team

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Eligibility criteria

Inclusion

3-25 years old at enrollment
With solid tumors of the chest, abdomen, and extremities including neuroblastic tumors, sarcoma including soft tissue and bone, kidney tumors, liver tumors, ovarian tumors, lung and pleural-based tumors, and intestinal tumors
OR-
Guardian or primary caregiver of patient 3-25 years old with one of the aforementioned tumors.

Exclusion

Patients who are known to be pregnant or prisoners.
  • Surgical resilience1 year

    Using smartwatches, we will assess motor activity by minutes spent being sedentary, active, or highly active, heart rate, and sleep duration and stages. This information will be collected before and after surgical resection. Data from the smartwatches syncs with Garmin connect using Fitabase which allows the study team to monitor and analyze the data. Results will be correlated with questionnaires responses, to see if there are digital biomarker patterns associated with return to baseline quality of life postoperatively.