Clinical Trial for Non-Healing Foot and Leg Ulcers

This study is looking at new ways to help non-healing diabetic foot ulcers (DFUs) and venous leg ulcers (VLUs) close. It compares standard care (like cleaning and dressing wounds) to standard care plus two different human placental membrane products, called AM/Single and AM/Double. The goal is to see if these products help ulcers heal faster over 12 weeks. You may be able to join if you are at least 18 years old, have type 1 or 2 diabetes, and have a DFU or VLU within a specific size range. The study is currently recruiting about 177 participants, but its exact status is unclear.

Study design
This is a multicenter, randomized controlled study designed to compare different treatments. It plans to enroll about 177 participants.
What's involved
You would receive weekly treatments, which include standard care (cleaning, debridement, and managing moisture or compression) and possibly applications of AM/Single or AM/Double, for up to 12 weeks.
Compensation
Not stated in the trial record.
Follow-up
The primary goal is to measure ulcer closure over 12 weeks.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06674980

Clinical Trial Assessing Human Placental Membrane Products and Standard of Care Versus Standard of Care in Nonhealing DFUs and VLUs

Recruiting
NAAges 18+InterventionalTreatment
C5 Biomedical
~177 participants
Updated 2024-12-27 on ClinicalTrials.gov
What's tested:Standard of Care - DFUAM/Single - DFUAM/Double - DFUStandard of Care - VLUAM/Single - VLUAM/Double - VLU

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Determine the percentage of subjects achieving complete closure of target ulcer over 12 weeks.
Measured over 1-12 weeks
Pathologic Processes
Diabetes Mellitus
Glucose Metabolism Disorders
Metabolic Diseases
Endocrine System Disease
Diabetic Angiopathies
Vascular Diseases
Cardiovascular Diseases
Leg Ulcer
Skin Ulcer
Skin Diseases
Diabetes Complications
Diabetic Neuropathies
Foot Diseases
Diabetic Foot
Foot Ulcer
Diabetes Mellitus, Type 2
Ulcer
Foot Ulcer Unhealed
1 sites across 1 states
Louisiana1
  • Thomas Serena, MD · PRINCIPAL_INVESTIGATOR · SerenaGroup, Inc.

Opens a ready-to-send draft in your own email app — review before sending.

  • Determine the percentage of subjects achieving complete closure of target ulcer over 12 weeks.1-12 weeks

    The proportion of subjects achieving complete wound closure of target ulcer.