Meditative Neurofeedback for Depression

This study is testing a new approach called MediNF (meditative neurofeedback) for people with moderate depression. MediNF involves 10 sessions of breath-focused meditation with real-time feedback on your brain activity to help improve performance. The study aims to see if this intervention can significantly reduce symptoms of depression. You might be able to join if you are 18 or older, have moderate depression, and do not have active substance abuse, psychotic disorders, bipolar disorder, or acutely suicidal behaviors. Researchers will measure your depression symptoms using the PHQ9 (a questionnaire) after 8 weeks to see how well MediNF works. The current status of this study is unclear.

Study design
This is an open-label, single-arm study, meaning all 27 participants will receive the MediNF intervention, and both you and the researchers will know what treatment you are getting.
What's involved
You would participate in 10 sessions of breath-focused meditative practice with frontal brain connectivity neurofeedback. Your depression symptoms will be measured at 8 weeks.
Compensation
Not stated in the trial record.
Follow-up
Your depression symptoms will be measured at 8 weeks after starting the intervention.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06675240

Meditative Neurofeedback for Depression

Recruiting
NAAges 18+InterventionalTreatment
University of California, San Diego
~27 participants
Updated 2026-01-14 on ClinicalTrials.gov
What's tested:MediNF

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
PHQ9
Measured over 8 weeks
Depression - Major Depressive Disorder
Depression Disorders
1 sites across 1 states
California1

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

moderate depression per PHQ9 symptom ratings

Exclusion

active substance abuse/dependence
psychotic disorders
bipolar disorder
displaying acutely suicidal behaviors
  • PHQ98 weeks

    Depression Symptoms on the Patient Health Questionnaire 9-item (PHQ9) scale, min 0 max 27 with lower scores representing better outcome