Testing the SiS4 App for Nondaily Smokers

This study is testing a new smartphone app called "Smiling instead of Smoking" (SiS) to help people who smoke less than daily quit. The SiS app uses positive psychology exercises and tools to help you quit. You would use this app or another app called "QuitGuide" from the National Cancer Institute (NCI). We want to see if the SiS app helps people quit smoking and how it affects their attitudes toward smoking, urges, and overall well-being. You can join if you are 18 or older, smoke less than daily but at least weekly, have smoked 100+ cigarettes in your lifetime, want to quit, and own a smartphone. Success in this study means you report not smoking for 30 days.

Study design
This is a large study with 1,600 participants. It's a randomized clinical trial, meaning you'll be randomly assigned to use either the SiS app or the QuitGuide app.
What's involved
You will use the assigned app for 7 weeks, starting one week before your chosen quit date. You will also complete online surveys at the start and at 2 weeks, 6 weeks, 3 months, 6 months, and 12 months after your quit date.
Compensation
Not stated in the trial record.
Follow-up
You will be followed for 12 months after your chosen quit date, with surveys at 2 weeks, 6 weeks, 3 months, 6 months, and 12 months.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06678243

Testing the mHealth App Intervention for Nondaily Smokers "SiS4"

Recruiting
NAAges 18+InterventionalTreatment
Massachusetts General Hospital
~1,600 participants
Updated 2025-06-11 on ClinicalTrials.gov
What's tested:Smiling instead of SmokingQuitGuide

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Self-reported 30-day point-prevalence abstinence (PPA) from smoking
Measured over Baseline, 2, 6, 12, 24, and 52 weeks
Smoking Cessation
1 sites across 1 states
Massachusetts1
  • Bettina Hoeppner, Ph.D., M.S. · PRINCIPAL_INVESTIGATOR · Massachusetts General Hospital

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  • Self-reported 30-day point-prevalence abstinence (PPA) from smokingBaseline, 2, 6, 12, 24, and 52 weeks

    The 30-day point prevalence abstinence (PPA) is a self-reported measure recorded at 6 months post-quit. In each online survey participant will be asked to report, "During the past 30 days, on how many days did you smoke". If a participant does not report abstinence, they will be asked to indicate how many cigarettes they smoked per day on the days they smoked and whether they are seriously thinking of quitting smoking. The investigators will also include the question, "have you been abstinent during the past 30 days?" (yes/no). In order to get to this question, participants will answer have to answer prior questions as, " I do not smoke at all", and "yes", they have been abstinent during the past 7 days. The investigators will code a binary indicator for self-reported 30-day point prevalence abstinence (yes/ no).