Rising Tide: Amniotic Tissue Treatments for Diabetic Foot Ulcers

This study, called "Rising Tide," is looking at new ways to treat chronic diabetic foot ulcers (DFUs). Researchers are testing different types of placental-based allografts (tissue from a donor, in this case, from the placenta) called Amnion/Chorion/Amnion, Amnion/Chorion, and Amnion/Amnion. These treatments will be given along with standard care, and compared to standard care alone. The main goal is to see how many DFUs heal after 12 weeks of treatment. You might be able to join if you are at least 18 years old and have a DFU that meets specific criteria. The study plans to enroll 240 people, but its current status is unclear.

Study design
This interventional study plans to enroll 240 participants. It compares different placental-based allografts plus standard care to standard care alone.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint is measured at 12 weeks, indicating follow-up for at least this duration.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06681428

Rising Tide - Amniotic Tissue(s) Treatments for Chronic Diabetic Foot Ulcers

Recruiting
NAAges 18+InterventionalTreatment
Tides Medical
~240 participants
Updated 2025-02-10 on ClinicalTrials.gov
What's tested:Allograft

At a glance

Recruiting sites
9 of 9 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Percentage of DFUs healed at 12 weeks
Measured over 12 Weeks
Diabetic Foot Ulcer (DFU)
Chronic Foot Ulcers
9 sites across 5 states
California4
Ohio2
Florida1
North Carolina1
Virginia1
  • David G Armstrong, DPM, MD, PhD · STUDY_CHAIR · Keck School of Medicine of USC
  • Frank Burrows, MBA, EMT, BCMAS, CWCA · STUDY_DIRECTOR · Tides Medical
Frank Burrows III, MBA, EMT, BCMAS, CWCA
Email the study team

Opens a ready-to-send draft in your own email app — review before sending.

  • Percentage of DFUs healed at 12 weeks12 Weeks

    Percentage of index ulcers (the ulcers being treated in the study) healed at 12 weeks