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Study on Liver Regeneration After Surgery Using Breath Samples

This study is looking for people who are planning to have a partial liver removal surgery for liver cancer or other liver diseases. Researchers want to see if measuring carbon monoxide in your breath can help understand how well your liver is growing back (regenerating) after surgery. You would provide breath samples before and after your surgery. The goal is to see if carbon monoxide levels in your breath are linked to how quickly and effectively your liver regenerates and functions. The study aims to enroll 125 participants, but its current recruitment status is unclear.

Study design
This is an interventional study that plans to enroll 125 participants.
What's involved
You would provide breath samples for carbon monoxide measurements before your liver surgery, and then again 4 hours and 24 hours after surgery.
Compensation
Not stated in the trial record.
Follow-up
Measurements will be taken pre-surgery, then 4 hours and 24 hours post-surgery.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06681818

Novel Method to Assess Hepatic Regeneration and Predict Hepatic Related Morbidity After Partial Hepatectomy

Recruiting
NAAges 18+InterventionalBasic science
Englewood Hospital and Medical Center
~125 participants
Updated 2025-07-23 on ClinicalTrials.gov
What's tested:carbon monoxide measurement via smokerlyzer

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
correlation of carbon monoxide levels in exhaled breath with quantity and quality of liver regeneration
Measured over measurements will be taken pre, then 4 hours and 24 hours post resection

Conditions

Liver Cancer Adult
Liver Regeneration

Explore related trials

Liver Carcinoma

Where it's being run

1 sites across 1 states
New Jersey1

Study leadership

  • Cherif Boutros, MD · PRINCIPAL_INVESTIGATOR · Englewood Hospital

Who to contact

Jamie Ketas
[email protected]
2018943418
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Patient plans to have partial liver resection for primary liver pathology or metastatic disease
Patient is able to comprehend and willing to sign the written consent form

Exclusion

Patients \< 18 years
Patients identified as members of a vulnerable population, except women of child bearing potential with negative pregnancy test

What this trial measures

  • correlation of carbon monoxide levels in exhaled breath with quantity and quality of liver regenerationmeasurements will be taken pre, then 4 hours and 24 hours post resection

    patients will be asked to donate exhaled breath into a smokerlyzer device