This 5-year study aims to better understand different types of prediabetes and type 2 diabetes based on how your body works (like insulin resistance). We want to see if certain treatments work better for specific types of diabetes. You might be eligible if you are 18-75 years old, have a BMI between 23 and 45 (or 22-45 for Asians), and have an HbA1c (a measure of blood sugar over time) between 5.7% and 8.0% without taking diabetes medications. We are testing three approaches: metformin (a common diabetes drug), GLP-1A (another type of diabetes medication), and following a Mediterranean diet. The main goal is to see how your HbA1c changes over time with these treatments. The study status is currently unclear.

Study design

This interventional study plans to enroll 200 participants. It will involve three treatment periods, each lasting 4 months, with a 3-month break between each treatment.

What's involved

You would go through an initial screening, followed by three treatment periods, each lasting 4 months, with 3-month washout periods in between. Your HbA1c will be measured at months 0, 4, 8, 11, 15, and 18.

Compensation

Not stated in the trial record.

Follow-up

Your HbA1c will be measured up to 18 months after the start of the study.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.