This study is looking at whether combining a low-FODMAP diet (a diet that limits certain carbohydrates that can cause digestive issues) with a medication called mirtazapine can better help people with Irritable Bowel Syndrome with Diarrhea (IBS-D) compared to just the low-FODMAP diet alone. Researchers want to see if this combination improves symptoms like abdominal pain and diarrhea. You might be able to join if you are between 18 and 70 years old, have IBS-D based on specific criteria, and score above 175 on the IBS-SSS questionnaire. The study will measure how much your IBS symptoms, abdominal pain, and stool form improve after 49 days. The current status of this study is unclear, and it plans to enroll 20 participants.

Study design

This is an interventional study, meaning participants will receive a specific treatment. It plans to enroll 20 participants.

What's involved

Participants will be told to use mirtazapine or a placebo, starting with 1 pill before bedtime for the first week, increasing to 2 pills in the second week, 3 pills in the third week, and 4 pills in the fourth week. Not specified in the trial record.

Compensation

Not stated in the trial record.

Follow-up

The primary outcomes, such as resolution of IBS, abdominal pain score, and stool form scale, will be measured at 49 days.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.