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Study on Cannabidiol (CBD) Oil and Driving Performance

This study is looking at how Cannabidiol (CBD) Oil affects driving in healthy adults aged 18-30. Researchers want to understand if different doses of CBD Oil (150mg or 300mg) or a placebo oil (a substance with no active drug) impact your driving performance, drowsiness, and thinking abilities. They will measure things like how well you stay in your lane, if you have any collisions, and how quickly you react to things while driving. To join, you need a current driver's license, to have driven recently, be able to read English, pass a drug test, and not be taking most daily prescription medications. The study is currently unclear on its recruitment status and plans to enroll 300 participants.

Study design
This is an interventional study designed as a randomized controlled trial (RCT) with 300 planned participants. It aims to investigate the effects of different doses of Cannabidiol (CBD) Oil and a placebo.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Your driving performance, collisions, and reaction time will be measured at 150 minutes after receiving the intervention.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06686914

The Effects of Cannabidiol on the Driving Performance of Healthy Adults by Dose and Sex

Recruiting
PHASE1Ages 18–30InterventionalBasic science
West Virginia University
~300 participants
Updated 2025-10-31 on ClinicalTrials.gov
What's tested:Cannabidiol (CBD) Oil 300mgCannabidiol (CBD) Oil 150mgPlacebo Oil

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Mean standard deviation of lateral position
Measured over 150 minutes post intervention
+3 more outcomes measured

Conditions

Cannabidiol Effects
Driving Performance

Explore related trials

Healthy

Where it's being run

1 sites across 1 states
West Virginia1

Study leadership

  • Toni M Rudisill, PhD · PRINCIPAL_INVESTIGATOR · West Virginia University

Who to contact

Toni M Rudisill, PhD
[email protected]
3042930687
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Possess a current drivers' license
Driven a motor vehicle at least once in the past 30 days
Able to read English
Test negative for all substances on a urine drug test and complete a test drive to ensure the absence of simulation sickness
Not taking any daily prescription medications (excluding birth control)
Not diagnosed with any serious chronic disease by a licensed healthcare provider (including but not limited to Alzheimer's and related dementias, Parkinson's disease or other neurodegenerative disorder, major depressive or anxiety disorder, schizophrenia or other serious mental illness, arrhythmias, cataracts, glaucoma, chronic obstructive pulmonary disease, diabetes, epilepsy, sleep apnea, and fibromyalgia)
Have an individual willing to drive them home after testing or be taken home by study staff after testing

Exclusion

Currently smoke, vape or use tobacco products, used CBD in the past 30 days
Used illegal drugs in the past 30 days (e.g., cocaine/crack, heroin, methamphetamine, 3,4-methylenedioxy-methamphetamine, inhalants, phencyclidine, lysergic acid diethylamide, psilocybin mushrooms, or marijuana)
Are pregnant or lactating at time of study

What this trial measures

  • Mean standard deviation of lateral position150 minutes post intervention

    The driving simulator will measure mean standard deviation which is the amount a driver is weaving within the lane during the drive. Ranges from 0 to infinity, with higher means indicating worse performance.

  • Number of collisions150 minutes post intervention

    The driving simulator will measure how many times a participant crashes into other vehicles, signs, pedestrians, etc. during the simulation. Ranges from 0 to infinity, with higher numbers indicating worse performance.

  • Mean reaction time to stimuli150 minutes post intervention

    The driving simulator will measure the mean reaction time (seconds) that it takes for a person to brake when exposed to stimuli. Ranges from 0 to infinity, with higher means indicating worse performance.

  • Percent of time driver is out of travel lane150 minutes post intervention

    The driving simulator will measure the percent of time that each driver spends driving outside their travel lane. Percent ranges from 0-100, with higher scores indicating worse performance.