Understanding How Childhood Experiences Affect Eating Habits
This observational study is looking into how experiences from childhood might influence eating behaviors and weight in adults. Researchers want to see if a belief that things are unpredictable (called an "unpredictability schema") is linked to how much food people eat and if they eat when they're not hungry. They will also look at how this belief is connected to physical activity and how the body processes sugar. You can join if you are a healthy adult between 18 and 60 years old. The study aims to find out if there's a connection between these childhood experiences and eating habits by Day 10 of the study.
- Study design
- This is an observational study involving 110 healthy volunteers or people with obesity. It is not testing a specific drug or intervention.
- What's involved
- You will have 3 clinic visits. These visits will include blood tests, answering questions about alcohol and tobacco use, body measurements, and an imaging scan to measure body fat. You will also wear a device to track physical activity.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary outcomes related to food intake and eating in the absence of hunger are measured at Day 10.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
NCT06690294
Assessing the Impact of Perceptions of Unpredictability on Objective Measures of Food Consumption and Metabolism
Not Yet Recruiting
Not specifiedAges 18–60ObservationalNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)Government-funded
~110 participants
Updated 2026-08-28 on ClinicalTrials.gov
At a glance
Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
To determine whether an association exists between unpredictability schema measures and ad libitum food intake.
Measured over Day 10
+1 more outcome measured
Conditions
Where it's being run
1 sites across 1 statesArizona1
Study leadership
- Tomas Cabeza De Baca, Ph.D. · PRINCIPAL_INVESTIGATOR · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
Do you actually qualify for this trial?
Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.
Eligibility criteria
Inclusion
Stated willingness to comply with all study procedures and availability for the duration of the study.
18-60 years of age.
Able to read and understand English proficiently (to be able to complete the multiple study questionnaires and instruments).
Exclusion
Diabetes
Fasting glucose \>= 126 mg/dl or HbA1c \>= 6.5% or
Self-reported history of type 1 or type 2 diabetes.
Endocrine disorders, such as
Self-reported history of Cushing's disease, pituitary disorders, or hypo- and hyperthyroidism
TSH \<0.1 or \>= 10 uIU/mL
Pulmonary disorders
Self-reported history of chronic obstructive pulmonary disease or other lung disease that which would limit ability to follow the protocol (investigator judgment)
Cardiovascular diseases,
Self-reported history of coronary heart disease, heart failure, arrhythmias, and peripheral artery disease that which would limit ability to follow the protocol (investigator judgment)
Liver disease,
Advanced liver disease (as determined by history, labs, exams, and patient self-report) that which would limit ability to follow the protocol (investigator judgment)
AST or ALT elevations \> 3 times upper limit of normal
Gastrointestinal Surgery
Self-reported history of bariatric surgery
Renal disease
Self-reported history of renal replacement therapy
Abnormal kidney function (defined as eGFR \<60 mL/min/1.73m\^2) determined at screening (eGFR values are computed using the 2021 CKD-epi equation)
Central nervous system disease:
Including self-reported history of previous history of cerebrovascular accidents, dementia, and neurodegenerative disorders
Infectious disease:
Self-reported history of active tuberculosis, HIV, chronic coccidiomycosis or other chronic or acute infections
For Females: pregnancy, \<=6 months postpartum, currently breastfeeding, or on birth control (i.e., ingested, injected or implanted; non-hormonal methods such as copper IUD will be allowed)
Measured weight: greater than or equal to 450 lb. (maximum weight allowed on the DXA scanning tables by the manufacturer)
Inability to provide informed consent.
Self-reported history of psychological conditions including (but not limited to), active psychosis, schizophrenia, eating disorders, or forms of mental incapacity that would be incompatible with safe and successful participation in this study.
Current use of medications/dietary supplements/alternative therapies known to alter energy metabolism.
Inability to consume provided food during ad libitum food intake or snack food test based on a food allergy or intolerances or diet restrictions.
Alcohol Abuse as defined by \>= 8-point score on the Alcohol Use Disorders Identification Test (AUDIT) questionnaire will be an exclusion criterion.
Current use of tobacco products that exceed "Very Low Dependence" on the Fagerstrom Test for Nicotine Dependence Tool (score greater than 2) will be an exclusion criterion.
What this trial measures
- To determine whether an association exists between unpredictability schema measures and ad libitum food intake.Day 10
Ad libitum Food Intake (kcal) measured from a buffet meal task.
- To determine whether an association exists between the unpredictability schema and experience scores and eating in the absence of hungerDay 10
Eating in the absence of hunger (kcal) from a snack food taste test.