Vaginal Changes After CO2 Laser for Genitourinary Syndrome of Menopause
This study is looking at how CO2 laser treatment affects the vagina in women with Genitourinary Syndrome of Menopause (GSM). GSM is a condition caused by lower estrogen levels after menopause, leading to symptoms like vaginal dryness and painful intercourse. The CO2 laser is being explored as a non-hormonal treatment option for these symptoms. Researchers will use a special device called Optical Coherence Tomography (OCT) to measure changes in vaginal tissue, specifically vaginal epithelial thickness and blood vessel density. They want to see if the CO2 laser helps improve these measurements. You can join if you are a woman aged 18 or older, have GSM, and are willing to use vaginal laser therapy without other GSM treatments during the study. The study plans to enroll 50 participants, but its current recruitment status is unclear.
- Study design
- This is an interventional study, meaning participants will receive a specific treatment. It plans to enroll 50 women.
- What's involved
- Measurements will be taken once a month for the first three months, then every three months for one year. This involves using an OCT device in the vaginal canal.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for one year after the initial three months of monthly measurements.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Vaginal Changes After CO2 Laser
At a glance
Conditions
NCT06691178
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
Beckman Laser Institute
Irvine, Californiastudy coordinator listed
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- Felicia Lane, MD · PRINCIPAL_INVESTIGATOR · University of California, Irvine
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- Vaginal epithelial thicknessMeasurements will be obtained once a month for the first three months. Measurements will be obtained at subsequent follow up visits every 3 months for 1 year.
OCT measurement of vaginal epithelial thickness
- Blood vessel densityMeasurements will be obtained once a month for the first three months. Measurements will be obtained at follow up visits every 3 months for 1 year.
OCT measurement of blood vessel density