This study is testing if giving saline (salt water) through an intrauterine pressure catheter (IUPC), a small tube placed in the uterus, can help prevent severe postpartum hemorrhage (PPH), which is heavy bleeding after childbirth. You might be able to join if you are at least 18 years old, are pregnant with one baby (singleton) at 34 weeks or more, are in labor, and have a medium or high risk for PPH. The study aims to see if this treatment can reduce the number of people who experience significant blood loss (1,500 mL or more), need blood transfusions, or require a hysterectomy (removal of the uterus) after delivery. The study plans to enroll about 700 participants, but its current status is unclear.

Study design

This is an interventional study planning to enroll 700 participants. It is designed to compare the effects of saline delivered via an IUPC.

What's involved

If you participate, an IUPC will be placed after your water breaks or at 4 cm dilation. You will receive a 300cc bolus of normal saline, followed by a continuous rate of 100 cc/hr until delivery.

Compensation

Not stated in the trial record.

Follow-up

Researchers will track outcomes like blood loss, transfusions, and hysterectomy from delivery admission to discharge (about 3 days post-delivery) or up to 12 weeks post-delivery.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.