Observational Study on Heart Health in Myelodysplastic Syndromes

This study is looking at why people with myelodysplastic syndromes (MDS), a type of blood cancer, might be more likely to develop heart problems. Researchers want to identify specific proteins in the blood, called inflammatory markers, that could help predict these heart issues. By understanding these markers better, the goal is to find new ways to detect and manage heart disease risks in people with MDS. You can join if you are at least 18 years old, have a confirmed MDS diagnosis, and are expected to live for at least 6 months. The study aims to enroll 30 participants. The main goal is to measure how these inflammatory markers change in your blood over 6 months.

Study design
This is an observational study, meaning you won't receive any new treatments. It plans to include 30 adult participants with Myelodysplastic Syndromes.
What's involved
You will have an initial visit, then weekly visits for 3 weeks, followed by monthly visits for 5 months. At each visit, you will provide a blood sample after not eating overnight.
Compensation
Not stated in the trial record.
Follow-up
Your blood markers will be measured over 6 months.

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NCT06692894

Defining Inflammatory Markers of Cardiovascular Disease in Patients With Myelodysplastic Syndromes

Recruiting
Not specifiedAges 18+Observational
University of Vermont
~30 participants
Updated 2026-02-03 on ClinicalTrials.gov
What's tested:Observational

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Biologic Variability of Markers of Inflammation in the Blood
Measured over over 6 months
Myelodysplastic Syndromes, Adult
1 sites across 1 states
Vermont1

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Eligibility criteria

Inclusion

Age ≥18 years
Histologically confirmed diagnosis of MDS by bone marrow biopsy morphology, using the 2022 World Health Organization (WHO) classification for myeloid neoplasms
Eastern Cooperative Oncology Group (ECOG) performance status ≤3
Expected survival of at least 6 months
Ability to provide consent

Exclusion

Cases meeting 2022 WHO criteria of MDS with excess blasts 2 as initial diagnosis
Hematopoietic stem cell transplantation expected within 6 months
  • Biologic Variability of Markers of Inflammation in the Bloodover 6 months

    The within- and between-person biologic variability of an inflammation proteome over a period of 6 months