Whey Protein and Glucose Control in Prediabetes and Type 2 Diabetes

This study is looking at how consuming whey protein isolate affects blood sugar (glucose) levels in people with prediabetes or type 2 diabetes. Researchers want to see if taking whey protein isolate twice a day, once in the morning and once before dinner, can help control blood sugar and appetite. You might be able to join if you are between 50 and 70 years old, have a body mass index (BMI) between 25-45 kg/m2, and have an HbA1c (a measure of average blood sugar over 2-3 months) between 5.7% and 7.5%. The study will measure changes in whole body protein turnover, oral glucose tolerance, and blood glucose after 7 days to see if the intervention is successful. The current status of this study is unclear.

Study design
This is an interventional study planning to enroll 40 participants. It uses a crossover design, meaning participants will receive both the whey protein isolate and a placebo at different times.
What's involved
You would participate in two separate 7-day periods, one with whey protein isolate and one with a placebo. During these periods, you would need to avoid alcohol, marijuana, and CBD products.
Compensation
Not stated in the trial record.
Follow-up
The primary measurements for the study are taken at 7 days.

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NCT06694155

Whey Protein Ingestion and Glucose Control in Pre- and Post Diabetic Individuals

Recruiting
NAAges 50–70InterventionalSupportive care
University of Arkansas
~40 participants
Updated 2026-04-06 on ClinicalTrials.gov
What's tested:Whey Protein Isolate CrossoverPlacebo

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Whole body protein turnover
Measured over 7 days
+2 more outcomes measured
Prediabetes / Type 2 Diabetes
1 sites across 1 states
Arkansas1

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  • Whole body protein turnover7 days

    Whole body protein turnover reflects the continual synthesis and breakdown of body proteins. It can be measured at a whole-body or tissue level using stable isotope methods.

  • Oral Glucose Tolerance Test7 days

    Oral Glucose Tolerance Test (OGTT) is used to screen for or diagnose diabetes. Normal blood values for a 75 gram OGTT are: Fasting -- 60 to 99 mg/dL (3.3 to 5.5 mmol/L), 1 hour -- Less than 200 mg/dL (11.1 mmol/L), 2 hours -- Less than 140 mg/dL (7.8 mmol/L) is normal.

  • Blood glucose7 days

    Continuous glucose monitoring means using a device to automatically estimate your blood glucose level, also called blood sugar, throughout the day and night for 7 days.