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Neurobehavioral Therapy for Epilepsy and Major Depressive Disorder

This study is testing an online group Neurobehavioral Therapy (NBT) with text messaging for Veterans who have both epilepsy and major depressive disorder (MDD). NBT is a type of behavioral therapy where you learn tools to help manage seizures and understand your environment better. The study aims to see if this online therapy is practical and acceptable to participants. Researchers will measure how many people enroll, how many stay in the study, and how often they attend the online sessions. To join, you must be an English-speaking Veteran, 18 or older, with home internet, a computer or tablet, a mobile device for texting, and an active diagnosis of major depressive disorder.

Study design
This is an interventional study with a planned enrollment of 16 participants. It is a single-arm study, meaning all participants receive the same intervention.
What's involved
Participants will have an introduction session and 12 weekly, 1-hour online sessions of Neurobehavioral therapy, lasting a total of 12 weeks.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoints are measured at 14 weeks after baseline, which is post-intervention.

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NCT06695767

Neurobehavioral Therapy For Epilepsy And Major Depressive Disorder

Recruiting
NAAges 18+Interventional
The University of Texas Health Science Center, Houston
~16 participants
Updated 2025-01-09 on ClinicalTrials.gov
What's tested:Neurobehavioral therapy

At a glance

Recruiting sites
2 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Enrollment rate
Measured over post intervention (14 weeks after baseline)
+4 more outcomes measured

Conditions

Major Depressive Disorder
Epilepsy

Explore related trials

Seizure DisorderUnipolar Depression

Where it's being run

2 sites across 1 states
Texas2

Study leadership

  • Melissa Fadipe, MSN, APRN, FNP-C · PRINCIPAL_INVESTIGATOR · The University of Texas Health Science Center, Houston

Who to contact

Melissa Fadipe, MSN, APRN, FNP-C
[email protected]
(713) 825-7237
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

English speaking veterans
has home internet access
has access to and familiarity in using a computer or tablet at least weekly
Asymptomatic patients with chronic conditions
has access to a mobile device with Short Message Service (SMS) text and picture capability
has an active clinical diagnosis of major depressive disorder based on the International Classification of Diseases, 10th version (ICD-10)
has an ICD-10 diagnosis of epilepsy with at least one seizure documented within the last five years

Exclusion

pregnancy
Veterans that have current suicidal ideation
have active psychosis; and have an ICD-10 diagnosis of psychogenic non-epileptic seizures or conversion disorder.

What this trial measures

  • Enrollment ratepost intervention (14 weeks after baseline)

    This is defined as the number enrolled divided by the number of eligible participants screened

  • Retention ratepost intervention (14 weeks after baseline)

    This is defined as the number completing the study/number enrolled at baseline

  • Session attendance rate (proportion of sessions attended)post intervention (14 weeks after baseline)
  • Homework completion rate (proportion of homework assignments completed)post intervention (14 weeks after baseline)
  • User satisfaction as assessed by The Participant Satisfaction Surveypost intervention (14 weeks after baseline)

    This is a 16 item questionnaire and the first 10 questions are scored from 1( strongly disagree)to 5(strongly agree) for a maximum score of 50, higher score indicating better outcome