NCT06697184

A Study to Investigate the Safety of Novel Dose Ramp-up Schedule(s) When Initiating Sonrotoclax in Participants Treated for Blood Cancers.

Recruiting
PHASE1Ages 18+InterventionalTreatment
BeOne Medicines
~258 participants
Updated 2026-06-08 on ClinicalTrials.gov
What's tested:SonrotoclaxZanubrutinib

At a glance

Recruiting sites
6 of 17 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Number of Participants who Experience Tumor Lysis Syndrome (TLS)
Measured over Up to approximately 4 months
Chronic Lymphocytic Leukemia
CLL
Mantle Cell Lymphoma
MCL
17 sites across 12 states
France3
Victoria2
Western Australia2
United Kingdom2
Florida1
Indiana1
Kansas1
Massachusetts1
  • Study Director · STUDY_DIRECTOR · BeOne Medicines

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  • Number of Participants who Experience Tumor Lysis Syndrome (TLS)Up to approximately 4 months

    TLS will be defined by Howard criteria during the schedule-limiting toxicity (SLT) evaluation window