Ovarian Tissue Cryopreservation for Fertility Preservation

This study is looking at ovarian tissue cryopreservation (freezing ovarian tissue) as a way to help young women preserve their fertility. Many cancer treatments, and treatments for conditions like rheumatoid arthritis and lupus, can harm a woman's ability to have children later. This study aims to understand how many patients choose to have their ovarian tissue frozen and when they decide to use it. You might be able to join if you are a female between 1 and 25 years old, have a new cancer diagnosis or a cancer that has returned, and your treatment plan includes certain types of radiation or high doses of cyclophosphamide. The main goal is to track how many patients use their frozen ovarian tissue and their age at that time, over a 10-year period.

Study design
This is an interventional study planning to enroll 40 female participants between 1 and 25 years old.
What's involved
Participants will have ovarian tissue removed through a laparoscopic procedure (a type of surgery using small incisions) under general anesthesia, ideally during another planned surgery.
Compensation
Not stated in the trial record.
Follow-up
The study will track the use of ovarian tissue and age of use for 10 years.

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NCT06710769

Ovarian Tissue Cryopreservation

Recruiting
NAAges 1–25Interventional
Phoenix Children's Hospital
~40 participants
Updated 2026-01-23 on ClinicalTrials.gov
What's tested:Ovarian tissue removal will be performed laparoscopically

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Percentage of patients who utilize their ovarian tissue and the age at which they use it will be evaluated. The number of patients who elect to have OTC will be analyzed over time to identify trends.
Measured over 10 years
Infertility, Female
1 sites across 1 states
Arizona1

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Eligibility criteria

Inclusion

Newly diagnosed or relapsed malignancy with proposed treatment regimen containing at least ONE (1) of the following:

Exclusion

Pregnancy or a patient who is currently breastfeeding
  • Percentage of patients who utilize their ovarian tissue and the age at which they use it will be evaluated. The number of patients who elect to have OTC will be analyzed over time to identify trends.10 years

    data will be investigated via qualitative analysis.