Extended TARPEYO® Treatment for IgA Nephropathy

This study is looking at whether taking TARPEYO® (a medication for IgA nephropathy) for a longer time is helpful and safe. You could join if you are an adult (18 or older) with IgA nephropathy (a kidney disease) that has been confirmed by a biopsy, and you have already completed 9 months of TARPEYO® 16 mg once daily. The main goal is to see if continuing TARPEYO® helps reduce protein in your urine (a sign of kidney damage) after 6 months compared to when you started the extended treatment. The study is currently unclear on its recruitment status and plans to enroll about 60 people.

Study design
This is an interventional study, meaning participants will receive a specific treatment. It aims to enroll about 60 adult participants.
What's involved
You would take part in this study for about 19 months. This includes having urine tests, blood samples taken, and physical examinations.
Compensation
Not stated in the trial record.
Follow-up
After the treatment period, there will be a 3-month follow-up period.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06712407

Efficacy and Safety of Extended TARPEYO® Treatment Beyond 9 Months in Adult Patients With Primary IgA Nephropathy

Recruiting
PHASE4Ages 18+InterventionalTreatment
Calliditas Therapeutics AB
~60 participants
Updated 2026-02-05 on ClinicalTrials.gov
What's tested:TARPEYO®

At a glance

Recruiting sites
38 of 38 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Ratio of Urine Protein to Creatine Ratio (UPCR) at 6 months compared to Baseline
Measured over 6 months
IgA Nephropathy
38 sites across 21 states
Texas8
California5
Georgia3
New York3
Florida2
New Mexico2
Alabama1
Arizona1
  • Krassimir Mitchev · STUDY_DIRECTOR · Calliditas Therapeutics

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  • Ratio of Urine Protein to Creatine Ratio (UPCR) at 6 months compared to Baseline6 months

    The outcome is measured as UPCR (based on 24-hour urine collection) at 6 months following the first dose of TARPEYO® trial treatment compared to study Baseline. Ratio being UPCR at 6 months in g/gram divided with UPCR at Baseline in g/gram.