Back to search results

Comparing Thulium Lasers for Kidney Stone Treatment

This study is comparing two laser systems, the Thulio pulsed Thulium:YAG (p-Tm:YAG) and the Thulium Laser Fiber (TFL), to see how well they break up kidney stones during a procedure called ureteroscopy. The Thulio p-Tm:YAG is a newer laser that may have benefits like less stone movement and smaller stone fragments. We are looking for 50 participants, aged 18 and older, who have kidney stones between 7 and 20 mm and are suitable for ureteroscopy. The main goal is to see which laser uses less energy to break up a given volume of stone. The study status is currently unclear.

Study design
This interventional study plans to enroll 50 participants to compare two different laser systems for kidney stone treatment.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed up with imaging 6-12 weeks after enrollment.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06721975

Thulium Fiber Laser (TFL) vs Thulio Pulsed Thulium:YAG (p-Tm:YAG)

Recruiting
NAAges 18+InterventionalTreatment
University of California, San Diego
~50 participants
Updated 2026-07-09 on ClinicalTrials.gov
What's tested:Thulio pulsed Thulium:YAG (p-Tm:YAG)Thulium Laser Fiber (TFL)

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
The amount of energy used per given stone volume
Measured over From enrollment to the follow up imaging at 6-12 weeks

Conditions

Kidney Stones
Nephrolithiasis

Explore related trials

Nephrolithiasis

Where it's being run

1 sites across 1 states
California1

Who to contact

Jade McDermott, BS
[email protected]
858-777-9721
Email the study team

Opens a ready-to-send draft in your own email app — review before sending.

Do you actually qualify for this trial?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

Solitary renal stone 7 to 20 mm in size or in the case of multiple stones the conglomerate diameter (additive maximal diameter of all stones on axial imaging of computed tomography) of 7-20 mm is required
Must be a suitable operative candidate for flexible ureteroscopy per American Urological Association guidelines
Must be able to give consent
Bilateral ureteroscopy will be permitted but only the first side (per surgeon discretion) will be included in the study
Surgeons participating in the study must be urological attending surgeons or fellows with subspecialty training in Endourology

Exclusion

Concomitant stones in the ureter
Prior ipsilateral upper urinary tract reconstructive procedures or history of ipsilateral ureteral stricture
Prior radiotherapy to the abdomen or pelvis
Neurogenic bladder or spinal cord injury
Pregnancy
Untreated UTI

What this trial measures

  • The amount of energy used per given stone volumeFrom enrollment to the follow up imaging at 6-12 weeks

    The primary object is to assess the stone dusting ablation efficiency - efficiency will be defined by amount of laser energy used per stone volume (Joules/mm3)