Understanding How Medical Information Influences Treatment Choices for Advanced Cancer

This observational study, called CHOICES, is looking at how the way medical information is shared affects treatment decisions for people with advanced cancer. Researchers want to understand how different details, like risks, benefits, time commitment, and costs, influence your preference for palliative systemic therapy (treatment to relieve symptoms and improve quality of life). You could join if you are 18 or older, have advanced solid tumor or aggressive lymphoma, have been seen at MD Anderson Cancer Center Thoracic and Lymphoma Oncology Clinics for a follow-up, and have had at least two lines of palliative systemic cancer therapies. The study will measure overall survival (how long people live) over about one year. This study is not testing a new drug, but rather how information is presented.

Study design
This is an observational study with 400 participants. It uses a randomized case vignette design, meaning you'll respond to hypothetical scenarios rather than your own health situation.
What's involved
You will complete about 16 questionnaires with questions about your quality of life, anxiety, health, and case scenarios.
Compensation
Not stated in the trial record.
Follow-up
Overall survival will be measured through study completion, which is an average of 1 year.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06722846

Communicating Health Options to Inform Care and Empower Strategic Care Planning (CHOICES): A Multi-layer Randomized Case Vignette Study.

Recruiting
Not specifiedAges 18+Observational
M.D. Anderson Cancer Center
~400 participants
Updated 2026-08-31 on ClinicalTrials.gov
What's tested:Randomized Case Vignette Study

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Overall Survival (OS)
Measured over Through study completion; an average of 1 year.
Health Options
Strategic Care Planning

NCT06722846

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • MD Anderson Cancer Center

    Houston, Texasstudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • David Hui, MD · PRINCIPAL_INVESTIGATOR · M.D. Anderson Cancer Center

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Eligibility criteria

Inclusion

Age 18 or greater
Seen at MD Anderson Cancer Center Thoracic and Lymphoma Oncology Clinics for a follow-up visit
Been treated with at least 2 lines of palliative systemic cancer therapies

Exclusion

Diagnosis of cognitive impairment or dementia requiring a surrogate decision maker
Non-English speaking
  • Overall Survival (OS)Through study completion; an average of 1 year.

    Progression Free Survival (PFS)