Low Dose Naltrexone for Central Neuropathic Pain in Spinal Cord Injury
This study is looking at how well a medication called naltrexone, given in a low dose (4.5mg daily), works for people who have central neuropathic pain (nerve pain from the brain or spinal cord) due to a spinal cord injury. Researchers want to see if naltrexone can reduce pain and improve your quality of life. You might be able to join if you are at least 18 years old, had a traumatic spinal cord injury (in the neck or chest area) more than six months ago, and have central neuropathic pain related to your injury. The study is currently unclear on its recruitment status and plans to enroll 10 participants.
- Study design
- This is a pilot study without a comparison group, meaning all participants will receive the low dose naltrexone. It is designed to gather information for a larger future study.
- What's involved
- You would take a 4.5mg naltrexone pill daily for 12 weeks. You will also keep daily medicine and sleep logs, and have regular virtual check-ins with the study team.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary goal is to evaluate the treatment's effect from enrollment to the end of treatment at 12 weeks.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Treating Central Neuropathic Pain With Low Dose Naltrexone for People With Spinal Cord Injury
At a glance
Conditions
Where it's being run
1 sites across 1 statesWho to contact
This trial hasn't published a contact. View it on ClinicalTrials.gov
What this trial measures
- Evaluate LDN in the treatment of CNP after SCIFrom enrollment to the end of treatment at 12 weeks
Generate initial data to calculate an effect size of LDN in the treatment of CNP in SCI. This will be utilized to plan a randomized control trial and submit for extramural funding.