Physical and Cognitive Aging Study in Older Adults

This observational study is looking for 100 older adults, including Hispanic Americans, to understand how physical activity and thinking skills change over time. Researchers want to see if it's possible to recruit and keep participants in a long-term study, and to gather early information on how physical and mental aging are connected. You would not receive any specific treatment or intervention in this study. The main goal is to see how well they can recruit people for this type of study over one year. To join, you should be between 55 and 85 years old, have at least an 8th-grade education, and live in the community. Hispanic Americans who identify as such and report Spanish as their primary language are also included. You should not have signs of dementia or mild cognitive impairment.

Study design
This is an observational study aiming to enroll 100 participants, split evenly between Hispanic American and non-Hispanic American adults. It is not a treatment study, but rather observes participants over time.
What's involved
You would have an initial visit to check eligibility and cognitive function, followed by a second visit to assess physical fitness and activity. These visits would be repeated about one year later.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed up for one year after their initial visits.

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NCT06726616

Physical and Cognitive Aging Study in Older Adults

Recruiting
Not specifiedAges 55–85Observational
University of Florida
~100 participants
Updated 2026-06-04 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Rate of recruitment
Measured over From recruitment to follow-up (1-year)
Older Adults (65 Years and Older)
Hispanic Americans
Cognitive Aging
Aging, Healthy
Exercise
1 sites across 1 states
Florida1

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Eligibility criteria

Inclusion

Self-identify as Hispanic American
Report Spanish as primary language • No evidence of dementia or mild cognitive impairment based on cognitive screening \[i.e., Montreal Cognitive Assessment (MoCA) administered during Visit 1; ≥26 among non-Hispanic White, ≥25 among Hispanics, ≥24 among non-Hispanic Blacks (Milani et al., 2018)\]

Exclusion

Inability to provide informed consent
Artificial joint or severe disability that would make it impossible or contraindicated performing the isokinetic test
Sensory loss (vision, hearing) or motor deficits that would preclude participation in the experimental tasks or neuropsychological assessment
Previous major strokes or other known significant brain abnormalities or diseases affecting the brain and/or cognition (e.g., Parkinson disease, multiple sclerosis, seizure disorder, brain surgery, moderate TBI, REM Behavior Sleep Disorder, untreated sleep apnea, etc.)
Unstable and uncontrolled medical conditions (metastatic cancer, HIV, moderate-severe kidney disease, uncontrolled diabetes, uncontrolled hypertension, severe cardiac disease, etc.). No current cancer diagnosis.
Current or past history of major psychiatric disturbance including schizophrenia, or active psychosis, bipolar disorder, current major depressive episode, current alcohol or substance abuse or history thereof within the past six months
Use of antipsychotics, sedatives, or other medications with significant anticholinergic properties (due to potential influence on memory)
Use of prescribed 'memory enhancing' medications, such as Aricept or Namenda
Previous participation in a cognitive or physical activity training study within the last 6 months or current involvement in another study involving cognitive, physical or other intervention at the time of enrollment
  • Rate of recruitmentFrom recruitment to follow-up (1-year)

    Recruiting \> 80% participants (50 Hispanic American and 50 non-Hispanic American adults) for a longitudinal aging study.