Cognitive Rehabilitation for Veterans with Depression

This study is for Veterans aged 18 and older who have Major Depressive Disorder (MDD) and are experiencing difficulties with memory, attention, or concentration. You must have received treatment for MDD at the Portland VA within the past year and have moderate or greater depressive symptoms. The study is testing two behavioral interventions: Motivationally Enhanced Compensatory Cognitive Training for Major Depressive Disorder (ME-CCT-MDD) and Goal-focused Supportive Contact. ME-CCT-MDD helps you learn strategies to improve your thinking skills, while Goal-focused Supportive Contact focuses on setting and achieving personal goals. Researchers want to see if these programs are practical and well-received by participants. The study aims to enroll 24 participants.

Study design
This is an interventional study comparing two behavioral interventions. It plans to enroll 24 participants.
What's involved
You would participate in an 8-week group-based behavioral intervention, meeting for 2 hours per week. Assessments will occur at enrollment and within two weeks after the 8-week treatment.
Compensation
Not stated in the trial record.
Follow-up
Participants will be assessed at the end of the 8-week treatment and again within two weeks post-treatment.

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NCT06728774

Cognitive Rehabilitation for Veterans With MDD-related Cognitive Functioning Deficits

Recruiting
NAAges 18+InterventionalTreatment
Portland VA Medical Center
~24 participants
Updated 2025-06-06 on ClinicalTrials.gov
What's tested:Motivationally Enhanced Compensatory Cognitive Training for Major Depressive Disorder (ME-CCT-MDD)Goal-focused Supportive Contact

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Recruitment Rate
Measured over From enrollment to the end of treatment at 8 weeks
+5 more outcomes measured
Major Depressive Disorder (MDD)
Cognitive Dysfunction
1 sites across 1 states
Oregon1
  • Maya O'Neil, PhD · PRINCIPAL_INVESTIGATOR · Portland VA Medical Center
  • Joren Adams · PRINCIPAL_INVESTIGATOR · Portland VA Medical Center

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  • Recruitment RateFrom enrollment to the end of treatment at 8 weeks

    Number of participants included from eligible Veterans; Recruitment will be deemed feasible if investigators successfully screen 50% of Veterans referred to the study for eligibility and enroll 75% of screened Veterans who meet all study inclusion criteria.

  • Study RetentionFrom enrollment to the second assessment (within 2 weeks post-treatment)

    Retention will be deemed successful if the investigators achieve 80% completion for post-treatment assessments.

  • Rate of Intervention CompletionFrom enrollment to the end of treatment at 8 weeks

    Percentage of participants that complete the 8-week intervention.

  • Feasibility of Testing ProceduresFrom enrollment to the second assessment (within 2 weeks post-treatment)

    Percentage of participants where follow-up visit was completed.

  • Feasibility of data collection methodsFrom enrollment to the second assessment (within 2 weeks post-treatment)

    Percentage of participants with complete data sets.

  • Acceptability, by participant reportFrom enrollment to the second assessment (within 2 weeks post-treatment)

    Treatment will be deemed acceptable if ≥ 70% of Veterans score ≥ 12 on the Acceptability of Intervention Measure (AIM).