Back to search results

Exploring Brain Health Markers with DELPHI-MD

This study is looking into new ways to understand brain health using a special device called DELPHI-MD. This device combines two non-invasive techniques: transcranial magnetic stimulation (TMS), which uses magnetic pulses to gently stimulate parts of your brain, and electroencephalography (EEG), which records your brain's electrical activity. Researchers want to see how the information from DELPHI-MD compares to other measurements of brain health, like behavioral tests and fMRI scans, that are collected in a separate study called The BrainHealth Project (NCT04869111). You can join if you are already participating in the imaging part of The BrainHealth Project, are between 22 and 100 years old, speak English, and can use a computer. The main goal is to see how the DELPHI-MD measurements relate to your BrainHealth Index over up to one year.

Study design
This is an interventional pilot study with a planned enrollment of 63 participants. It is exploring neurophysiological markers of brain health.
What's involved
You will complete two in-person sessions using the DELPHI-MD device, scheduled to align with your existing imaging appointments.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint is measured up to one year.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06731452

Exploring Neurophysiological Markers of Brain Health

Recruiting
NAAges 22+InterventionalBasic science
The University of Texas at Dallas
~63 participants
Updated 2025-09-16 on ClinicalTrials.gov
What's tested:Strategic Memory Advanced Reasoning Training teaches meta-cognitive strategies for individuals to apply to their daily lives for improved performance

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Correlation of DELPHI-MD Output Measures with the online BrainHealth Index
Measured over Up to one year

Conditions

Healthy Lifestyle
Health-Related Behavior

Explore related trials

Healthy Volunteers

NCT06731452

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Center for BrainHealth at The University of Texas at Dallas

    Dallas, Texasstudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Study leadership

  • Sandra Chapman, PhD · PRINCIPAL_INVESTIGATOR · The University of Texas at Dallas

Who to contact

Erin Venza, MS
[email protected]
972-883-3208
Email the study team

Opens a ready-to-send draft in your own email app — review before sending.

Want this trial checked against your situation?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

Must be an active brain imaging participant in The BrainHealth Project (NCT04869111)
Minimum age of 22
Fluent in English
Able to read \& hear information over a computer
Must pass an MRI safety screener to assess the presence of contraindicators for MRI compatibility (i.e., non-removable metal within/on the body, claustrophobia, pregnancy, non-correctable vision problems, head trauma, and CNS disease)or other standard requirements as determined by the Imaging Center.
Must pass a modified TMS Adult Safety Screen
Meet all criteria for study as determined by the study physician

Exclusion

A diagnosis of a neurodegenerative disease
A history of stroke, concussion, or brain injury that currently hinders them from functioning at their prior level
A diagnosis of autism spectrum disorder that currently hinders them from functioning independently.
Metallic brain implants or fragments (like a shunt, pacemaker, clips, coils, bullet fragments, cochlear implants)
Magnetically activated implants or electronically implanted devices
Medication pumps
Personal or family history of epilepsy, seizure(s), seizure disorder.
History of, or risk factors for syncope (fainting)
Report significant cognitive challenges
Report untreated health issues (like substance abuse, hypertension, hypo- or hyper-thyroidism)
Have claustrophobia

What this trial measures

  • Correlation of DELPHI-MD Output Measures with the online BrainHealth IndexUp to one year

    Evaluate the strength and significance of correlations between DELPHI-MD output metrics (e.g., cortical excitability, local/global mean field potentials, response amplitude, and latency) and scores from the BrainHealth Index. Unit of Measurement: Correlation coefficient (r). (Minimum value: -1.0, Maximum value: 1.0) (Higher value represents stronger correlation)