Meeting the Needs of Young Hispanic Autistic Children

This study is looking at two versions of a program called Culturally and Linguistically Responsive Pathways Parent-Mediated Intervention (CLR-Pathways) for young Hispanic autistic children. Researchers want to see if including a "mutual gaze procedure" in the program helps improve social communication, language, and everyday skills. You might be able to join if your child is Hispanic, between 18 and 42 months old, has autism, and your family has a low income. The study will measure changes in your child's social communication skills and how well they adapt to daily life. The current recruitment status is unclear.

Study design
This study will involve 200 Hispanic autistic children and their caregivers, who will be randomly assigned to one of two groups. One group will receive CLR-Pathways with mutual gaze strategies, and the other will receive CLR-Pathways without these strategies.
What's involved
Participants will attend 16 weekly coaching sessions, each lasting 1.5 hours, over approximately 18 weeks. There will also be three assessment visits, each lasting 2-3 hours.
Compensation
Not stated in the trial record.
Follow-up
Participants will have a follow-up assessment about three months after completing the intervention.

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NCT06733584

Meeting the Needs of Young Hispanic Autistic Children

Recruiting
NAAges 18–42InterventionalTreatment
The University of Texas at Dallas
~200 participants
Updated 2026-06-05 on ClinicalTrials.gov
What's tested:Culturally and Linguistically Responsive Pathways Parent-Mediated Intervention without Mutual GazeCulturally and Linguistically Responsive Pathways Parent-Mediated Intervention

At a glance

Recruiting sites
2 of 3 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in Respeto
Measured over At baseline (i.e., within two weeks prior to the start of intervention); Post-intervention (i.e., within two weeks after completing the intervention); At three-month follow-up
+5 more outcomes measured
Autism
3 sites across 2 states
Texas2
Kansas1
  • Pamela Rollins, EdD · PRINCIPAL_INVESTIGATOR · The University of Texas at Dallas

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Eligibility criteria

Inclusion

Children must be from a Hispanic family experiencing low income, defined as having an income-to-needs ratio of \< 320% of the federal poverty level, determined by their household size
Children must be between 18-42 months old at the start of the study
Children must have no other known neurological or genetic concerns or disorders determined by parent report
Children must receive a Calibrated Severity Score (CSS) of 4 or higher on the Autism Diagnostic Observational Schedule-2 (ADOS-2) administered by a qualified bilingual assessment associate
Families must have a primary home language of English and/or Spanish

Exclusion

Children who are from a family that is not Hispanic and/or does not have an income-to-needs ratio of \< 320% of the federal poverty level, determined by their household size
Children younger than 18 months or older than 42 months at the start of the study
Children whose parents report they have any other known neurological or genetic concerns or disorders
Children who receive a Calibrated Severity Score (CSS) lower than 4 on the ADOS-2
Families who do not have English or Spanish as a primary home language
  • Change in RespetoAt baseline (i.e., within two weeks prior to the start of intervention); Post-intervention (i.e., within two weeks after completing the intervention); At three-month follow-up

    Two dyadic measures of respeto will be coded using two items from the Joint Engagement Rating Inventory (JERI; Adamson et al., 2020). The Parent Calm Authority (PCA) subscale will measure the extent to which a parent influences the interaction using an assertive and confident yet gentle approach. The Child Affiliative Obedience (CAO) subscale will capture the child's affiliation, deference, and amenability to the parent's direction. These are scored using 7-point Likert scales (where 1 indicates no PCA or CAO, respectively). These measures will be derived from 12-minute naturalistic parent-child interaction video recordings. The interactions will be video-recorded from a wide-angle view as well as from hidden camera eyeglasses worn by the adult to capture the location and direction of the child's the location and direction of the child's eye gaze. The two streams of digitized videos will be time-linked and subsequently coded for measures of respeto.

  • Change in Social Communication SkillsAt baseline (i.e., within two weeks prior to the start of intervention); Post-intervention (i.e., within two weeks after completing the intervention); At three-month follow-up

    Change in the raw scores obtained on the Social, Speech and Symbolic composites of The Communication and Symbolic Behavior Scales- Developmental Profile (CSBS-DP; Wetherby \& Prizant, 2002) will be measured. Raw scores for the Social, Speech and Symbolic composites range from 0-64, 0-54 and 0-53 respectively (0 being the worst score). The CSBS-DP is a direct assessment of early social communication designed for children with a functional communication age between 6 months and 2 years.

  • Change in Adaptive FunctioningAt baseline (i.e., within two weeks prior to the start of intervention); Post-intervention (i.e., within two weeks after completing the intervention); At three-month follow-up

    Change in the raw scores obtained on the Communication, Daily Living, Socialization, and Motor Development domains of the Vineland Adaptive Behavior Scales, Second Edition (VABS-II; Sparrow et al., 2005) will be measured. Raw scores for these domains range from 0-252, 0-286, 0-224, 0-154 respectively (lower scores being worse outcomes). The VABS-II is a standardized parent report measure of adaptive functioning designed for individuals from birth to age 90.

  • Change in Social AttentionAt baseline (i.e., within two weeks prior to the start of intervention); Post-intervention (i.e., within two weeks after completing the intervention); At three-month follow-up

    The amount of time the child initiates eye gaze to the adult's eyes paired with positive affect will be measured (see Rollins et al., 2021 for a detailed description of this measure). This measure will be derived from 12-minute adult-child interaction video recordings wherein the child interacts with an unfamiliar adult during a semi-naturalistic play session. These interactions will be video-recorded from a wide-angle view as well as from hidden camera eyeglasses worn by the adult to capture the location and direction of the child's eye gaze. The two streams of digitized videos will be time-linked and subsequently coded for social orienting.

  • Change in Intentional CommunicationAt baseline (i.e., within two weeks prior to the start of intervention); Post-intervention (i.e., within two weeks after completing the intervention); At three-month follow-up

    Intentional communication will be measured using the Early Communication Indicator (EC Indicator; Greenwood et al., 2006). The EC Indicator yields a total weighted communication score weighting gestures and vocalizations as 1, single words as 2 and multiple words as 3. Each utterance will also be coded for the child's attentional focus when communicating (attention to object, attention to adult, coordinated attention to object and adult). This measure will be derived from 12-minute adult-child interaction video recordings wherein the child interacts with an unfamiliar adult during a semi-naturalistic play session. These interactions will be video-recorded from a wide-angle view as well as from hidden camera eyeglasses worn by the adult to capture the location and direction of the child's eye gaze. The two streams of digitized videos will be time-linked, orthographically transcribed at the level of the utterance, and subsequently coded for intentional communication.

  • Change in Expressive LanguageAt baseline (i.e., within two weeks prior to the start of intervention); Post-intervention (i.e., within two weeks after completing the intervention); At three-month follow-up

    Expressive language will be measured via the Moving Average Number of Different Words (MANDW) and Mean Length of Utterance in words (MLUw) calculated using the Systematic Analysis of Language Transcripts (SALT; Miller \& Iglesias, 2020) software. MANDW measures expressive vocabulary using a moving window to estimate the number of different words, controlling for variability in length across language samples. MLUw measures combinatorial language by calculating the ratio of main body words to the number of utterances produced. This measure will be derived from 12-minute adult-child interaction video recordings wherein the child interacts with an unfamiliar adult during a semi-naturalistic play session. These interactions will be video-recorded from a wide-angle view as well as from hidden camera eyeglasses worn by the adult to capture the location and direction of the child's eye gaze. The two streams of digitized videos will be time-linked and orthographically transcribed.