MMA Embolization for Refractory Chronic Migraine

This study is looking at a treatment called Middle Meningeal Artery (MMA) embolization using the TRUFILL n-BCA liquid embolic system for people with chronic migraine that hasn't responded to other treatments (refractory chronic migraine). The treatment involves blocking certain blood vessels in the head. Researchers want to see how safe and effective this treatment is. To join, you need to be between 18 and 65 years old, have been diagnosed with migraine before age 50, and have chronic migraine that started before age 64. The main goal is to see if the number of migraine days you experience changes after the treatment. The study is currently unclear about its recruitment status.

Study design
This is a feasibility study involving 70 participants across multiple centers. It is an interventional study, meaning participants will receive a specific treatment.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The study measures changes in migraine days over 28 days after the intervention.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06735833

MMA Embolization for Refractory Chronic Migraine

Recruiting
NAAges 18–65InterventionalDevice feasibility
Cerenovus, Part of DePuy Synthes Products, Inc.
~70 participants
Updated 2026-08-28 on ClinicalTrials.gov
What's tested:Middle Meningeal Artery embolization

At a glance

Recruiting sites
7 of 7 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change from baseline, in number of migraine days
Measured over over 28 days post study intervention
Migraine Disorders
7 sites across 6 states
New York2
California1
Connecticut1
Pennsylvania1
Tennessee1
West Virginia1

Opens a ready-to-send draft in your own email app — review before sending.

  • Change from baseline, in number of migraine daysover 28 days post study intervention