UC-MSC Cell Therapy Study for Systemic Lupus Erythematosus (SLE) Patients

This study is testing a cell therapy called UC-MSCs for adults with Systemic Lupus Erythematosus (SLE), also known as lupus. Researchers want to see if UC-MSCs can improve kidney function and reduce how active the disease is, while also checking if the treatment is safe and well-tolerated. You could join if you are between 18 and 75 years old and have been diagnosed with SLE based on specific medical criteria. The study will look at how many side effects occur over 168 days to understand the safety of UC-MSCs.

Study design
This is an interventional study with a planned enrollment of 10 participants. The phase of the study is not specified.
What's involved
Participants will receive a single dose of UC-MSCs, have physical exams, electrocardiograms (ECGs), and fill out surveys. You will also provide blood and urine samples for various lab tests at different visits.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 168 days to monitor for any treatment-emergent adverse events.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06737380

UC-MSC Cell Therapy Study for Systemic Lupus Erythematosus (SLE) Patients

Recruiting
PHASE1Ages 18–75InterventionalTreatment
LiveKidney.Bio
~10 participants
Updated 2025-09-11 on ClinicalTrials.gov
What's tested:Physical examinationElectrocardiogramSF-36 questionnaireClinical laboratory evaluations - SerologyClinical laboratory evaluations - BiochemistryClinical laboratory evaluations - Hematology

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Incidence of Treatment-Emergent Adverse Events
Measured over day 1 to day 168
SLE
Lupus
Systemic Lupus Erthematosus
Systemic Lupus Erythematosus
Systemic Lupus Erythematosus (SLE)
1 sites across 1 states
South Carolina1

Opens a ready-to-send draft in your own email app — review before sending.

  • Incidence of Treatment-Emergent Adverse Eventsday 1 to day 168

    Analysis for the primary endpoint will be descriptive in nature. safety and tolerability will be measured by the number of AEs and SAEs observed. Adverse event incidents will be summarized descriptively. The severity grade of each recorded AE, and their relationship to study treatment will be analyzed. The action taken and outcome will also be analyzed accordingly.