Computerized Decision Support for Familial Hypercholesterolemia

This study is testing if a computer alert system, called Alert-based computerized decision support, can help doctors better identify and manage Familial Hypercholesterolemia (FH), a genetic type of high cholesterol. The computer program will run within your electronic health record (EHR) and look for signs of FH. The main goal is to see if this alert increases how often doctors diagnose FH. You might be able to join if you are 18 or older, are seen in specific clinics at BWH (Brigham and Women's Hospital), and have a certain score (Dutch Lipid Clinic Network score of at least 3 points) that suggests you might have FH. You cannot join if you already have a documented FH diagnosis in your medical records. This study plans to include about 450 people.

Study design
This study is an interventional study, meaning it tests an intervention. It will involve a computer alert system running in two modes: a 'silent mode' for 6 months, followed by an 'alert mode' for 18 months.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The primary outcome, frequency of documented FH diagnosis, will be measured at 6 months.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06743659

Computerized Decision Support for Identification and Management of Familial Hypercholesterolemia

Recruiting
NAAll AgesInterventionalDiagnostic
Brigham and Women's Hospital
~450 participants
Updated 2025-09-18 on ClinicalTrials.gov
What's tested:Alert-based computerized decision support

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Frequency of documented FH diagnosis
Measured over 6 Months
Familial Hypercholesterolaemia

NCT06743659

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Brigham and Women's Hospital

    Boston, Massachusettsstudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

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Eligibility criteria

Inclusion

≥ 18 years old
seen in the BWH Endocrinology, Cardiovascular Medicine, and Primary Care Clinics
Dutch Lipid Clinic Network score of at least 3 points

Exclusion

a Familial Hypercholesterolemia diagnosis already documented in the EHR medical history, visit history, or problem list
  • Frequency of documented FH diagnosis6 Months

    We will review the medical history, visit diagnosis, and problem list sections of the Electronic Health Record (EPIC) to make this determination of diagnosis of Familial Hypercholesterolemia.