Clinical Validation of the Aptitude Medical Systems Metrix COVID-19 Test

This study is testing a new COVID-19 diagnostic test called the Aptitude Medical Systems Metrix COVID Test. This test is designed to detect the virus that causes COVID-19 using a special reader. Researchers want to see how well this test works compared to other FDA-approved COVID-19 tests. They are looking for about 1000 people aged 2 years and older who are currently experiencing a fever or other symptoms of a respiratory infection, like a cough or shortness of breath. The goal is to see if the Metrix COVID Test can accurately identify positive and negative COVID-19 cases in about 25 minutes. The study is currently unclear on its recruitment status.

Study design
This interventional study plans to enroll about 1000 participants. It will take place in simulated home environments set up near clinics.
What's involved
You would provide an anterior nasal (AN) swab sample for testing with the Metrix COVID Test. Comparator testing will also be performed.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoints are measured at 25 minutes.

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NCT06744660

Clinical Validation of the Aptitude Medical Systems Metrix COVID-19 Test

Recruiting
NAAges 2+InterventionalDiagnostic
Aptitude Medical Systems
~1,000 participants
Updated 2025-10-02 on ClinicalTrials.gov
What's tested:Aptitude Medical Systems Metrix COVID Test

At a glance

Recruiting sites
3 of 3 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Qualitative detection of RNA from SARS-CoV-2 and Measurement of Positive/Negative Percent Agreement with FDA-cleared comparator test
Measured over 25 minutes
COVID-19
COVID
3 sites across 2 states
Alabama2
Louisiana1

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  • Qualitative detection of RNA from SARS-CoV-2 and Measurement of Positive/Negative Percent Agreement with FDA-cleared comparator test25 minutes

    Qualitative detection of RNA from SARS-CoV-2 in unprocessed AN swab samples. Primary objective of this study is to evaluate the performance (positive percent agreement, negative percent agreement and 95% confidence intervals for upper and lower bounds) of the Metrix COVID/Flu Test for the qualitative detection of SARS-CoV-2 viral RNA using AN swab samples. Comparator testing will be performed to determine the status of each sample for comparison to results produced by the candidate test. Comparator testing will be performed to determine the infection status of each sample for comparison to results generated by the candidate test. The primary comparator for the study will be an FDA-cleared assay that detects SARS-CoV-2.