Observational Study on Lipoprotein Interactions and Platelet Function

This study is looking at how lipoproteins (particles in your blood that carry cholesterol) affect heart and blood vessel health in healthy people and those with lipid disorders (conditions like high cholesterol). Researchers want to understand how these lipoproteins work, not just how many there are, and how they might contribute to or prevent diseases like clogged arteries. The study aims to see how lipoproteins change in people with lipid disorders and how these changes affect blood clotting. There are no specific interventions being tested. To join, you need to be between 18 and 69 years old, able to give informed consent, and either a healthy volunteer or have abnormal lipid panels. The study is currently unclear on its recruitment status and plans to enroll 80 participants. Success will be measured by looking at the percentage of platelet aggregation after 5 years.

Study design
This is an observational study, meaning researchers will be watching and collecting information without giving any specific treatments. It plans to include 80 participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 5 years to measure the percentage of platelet aggregation.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06747000

Lipoprotein Interactions and Platelet Function in Healthy Individuals and Those With Lipid Disorders

Recruiting
Not specifiedAges 18–69Observational
The Miriam Hospital
~80 participants
Updated 2025-10-01 on ClinicalTrials.gov

At a glance

Recruiting sites
2 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Percentage of platelet aggregation
Measured over 5 years
Lipid Disorders
2 sites across 1 states
Rhode Island2

Opens a ready-to-send draft in your own email app — review before sending.

Do you actually qualify for this trial?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

Healthy volunteers
Abnormalities in lipid panels
Able to provide informed consent
Between the age of 18 and 69

Exclusion

Drug or alcohol abuse within 6 months or significant mental/psychological impairment
Current smokers
Subjects with known bleeding disorders (for example, hemophilia)
Subjects requiring regular transfusions for any reason
No ethnic/racial groups will be excluded
  • Percentage of platelet aggregation5 years

    Platelet aggregation area under the curve will be used as primary endpoint. Specifically, the percentage of platelet aggregation multiple time will be calculated to get area under the curve as a comprehensive marker for platelet aggregation response.