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NaviCam for Detecting Barrett's Esophagus

This study is testing a new way to detect Barrett's Esophagus using a device called NaviCam. The NaviCam is a small capsule you swallow that helps doctors get a good view of your esophagus (the tube that connects your mouth to your stomach). The goal is to see how well the NaviCam can find columnar lined epithelium, which is a change in the lining of the esophagus that can be a sign of Barrett's Esophagus. You might be able to join if you are an adult aged 22 or older, with or without Barrett's Esophagus, and have had an endoscopy within the last year. The study plans to enroll 57 people, but its current status is unclear.

Study design
This is an interventional study that plans to enroll 57 participants. It is not specified if it is randomized or blinded.
What's involved
You would swallow the NaviCam capsule with water while sitting upright. The procedure, from start to end, is expected to take up to 30 minutes.
Compensation
Not stated in the trial record.
Follow-up
The primary outcome is measured during the procedure, up to 30 minutes from start to end.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06748911

Navicam for Detection of Barrett's Esophagus

Recruiting
NAAges 22+InterventionalScreening
Mayo Clinic
~57 participants
Updated 2026-08-19 on ClinicalTrials.gov
What's tested:NaviCam Detachable String Capsule

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Detection of Columnar lined epithelium in the esophagus
Measured over From start of procedure to removal of capsule, assessed up to 30 minutes timeframe from start to end of procedure..

Conditions

Barrett's Esophagus

Explore related trials

Barrett Esophagus

Where it's being run

1 sites across 1 states
Florida1

Study leadership

  • Swathi Eluri · PRINCIPAL_INVESTIGATOR · Mayo Clinic

Who to contact

Stephanie McNew
[email protected]
904-953-5080
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Adults greater than or equal to 22 years of age with or without Barrett's Esophagus
All Patients:
Patients with Barrett's Esophagus:
Presence of at least 1cm of salmon colored mucosa with corresponding biopsies showing intestinal metaplasia who are treatment naïve and undergoing surveillance Or
Chronic Gastro Esophageal Reflux Disease (GERD) patients with at least 3 additional risk factors that meet Barrett's Esophagus screening criteria per latest clinical guidelines

Exclusion

Inability to comprehend or read the consent form
Have an oropharynx, esophageal, or gastro-esophageal tumor
Ongoing symptoms of dysphagia
Presence of active clinically significant stricture
History of stricture requiring dilation
Presence of pacemaker or implanted cardiac defibrillator
History of esophageal surgery with the exception of fundoplication
Pregnancy
History of surgery or obstructive process of the small bowel
BMI \> 38

What this trial measures

  • Detection of Columnar lined epithelium in the esophagusFrom start of procedure to removal of capsule, assessed up to 30 minutes timeframe from start to end of procedure..

    Detection of Columnar lined epithelium in the esophagus