Back to search results
NCT06749145

Deep Learning Enhanced Detection of Aortic Stenosis - The DETECT-AS-Diagnostic Study

Enrolling by Invitation
NAAges 70+InterventionalDiagnostic
Yale University
~410 participants
Updated 2025-11-26 on ClinicalTrials.gov
What's tested:Portable 1-lead electrocardiogramPoint-of-care ultrasoundAI-ECG risk algorithmAI-POCUS

At a glance

Recruiting sites
0 of 3 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Number of participants diagnosed with advanced aortic stenosis (AS) by transthoracic echocardiogram (TTE)
Measured over Until 12 months from the baseline visit

Conditions

Aortic Stenosis

Explore related trials

Aortic Valve Stenosis

Where it's being run

3 sites across 3 states
Connecticut1
New York1
Texas1

Study leadership

  • Rohan Khera, MD, MS · PRINCIPAL_INVESTIGATOR · Yale University

Who to contact

This trial hasn't published a contact. View it on ClinicalTrials.gov

Do you actually qualify for this trial?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

Age 70 years or older
Attending a routine outpatient primary care clinic at one of the three enrollment sites

Exclusion

Opted out of research studies
Non-English speaking
Urgent or emergent visits, defined as a visit for an illness or injury that needs attention quickly or is life-threatening
Any echocardiogram within 12 months of clinic visit
Prior history of moderate or severe AS
Prior history of aortic valve replacement or repair, including transcatheter and surgical AVR with either a bioprosthetic or mechanical valve
Presence of implantable cardiac devices, including permanent cardiac pacer, implantable cardioverter-defibrillator, or left ventricular assist device
Prior heart transplant
History of dementia
Documented life expectancy of \<1 year or current participation in hospice services.

What this trial measures

  • Number of participants diagnosed with advanced aortic stenosis (AS) by transthoracic echocardiogram (TTE)Until 12 months from the baseline visit

    The number of participants diagnosed with advanced AS by TTE at 12 months. Diagnosis of advanced AS is defined as diagnosis of moderate or severe AS as documented in the participant's electronic health record (EHR) at 12 months and adjudication of outcome via review of echocardiographic reports and videos performed by blinded members of the echocardiographic lab at the coordinating center.