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Tango for Chemotherapy-Induced Neuropathy in Breast Cancer Survivors

This study is looking into whether a special type of dance, called Adapted Argentine Tango (Tango), can help breast cancer survivors who have ongoing nerve damage (neuropathy) from chemotherapy. Neuropathy can cause problems like numbness, tingling, and increase the risk of falls. The Tango intervention involves 16 sessions over 8 weeks, led by trained dance instructors. Researchers want to see if Tango can improve how you feel (sensation) and your ability to do two things at once (dual-task function) after 4 weeks. You might be able to join if you are a breast cancer survivor, completed taxane-based chemotherapy at least 3 months ago, have symptoms of neuropathy, and show a potential fall risk. The study aims to enroll 140 participants.

Study design
This is an interventional study, meaning participants will receive a specific treatment. It plans to enroll 140 participants.
What's involved
Participants will take part in a 16-session Tango intervention, delivered over an 8-week period. You will also undergo testing to assess sensation and dual-task function.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoints for measuring success are at 4 weeks.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06749210

DAANCE FOR CHEMOTHERAPY-INDUCED NEUROPATHY

Recruiting
PHASE2Ages 40+InterventionalSupportive care
Ohio State University Comprehensive Cancer Center
~140 participants
Updated 2025-11-05 on ClinicalTrials.gov
What's tested:Tango

At a glance

Recruiting sites
2 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Patient-Reported Outcome (PRO) - CIN sensation
Measured over 4 weeks
+1 more outcome measured

Conditions

Cancer of the Breast
Chemotherapy-induced Neuropathy

Explore related trials

Breast CarcinomaChemotherapy-induced Neuropathy

Where it's being run

2 sites across 2 states
Connecticut1
Ohio1

Study leadership

  • Lise B Worthen-Chaudhari, PhD, MFA, CMES · PRINCIPAL_INVESTIGATOR · Ohio State University
  • Maryam B Lustberg, MD, MPH · PRINCIPAL_INVESTIGATOR · Yale University

Who to contact

Lise Worthen-Chaudhari, PhD, MFA, CMES
[email protected]
(1) + 614-293-6281
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Breast Cancer (BC) diagnosis of Stage I-IV including metastatic disease
completed taxane-based chemotherapy for BC at least 3 months ago (no limit on how long ago)
symptomatic for chemotherapy-induced neuropathy (self-report)
postural control score that indicates potential fall-risk
able to understand and comply with directions associated with testing and study treatments

Exclusion

pre-existing vestibular dysfunction
poorly controlled diabetes (hgA1C\>=8)
non-ambulatory (assistive and prosthetic devices allowed)
hearing impairment resulting in less than 10% hearing bilaterally
contraindication to participate in the experimental physical activity per the treating oncologist due to additional condition (e.g., herniated disc, unstable bone metastases)
currently in activity-based therapy (e.g., physical therapy, occupational therapy). May enroll if still meet eligibility criteria once activity-based therapy is complete.

What this trial measures

  • Patient-Reported Outcome (PRO) - CIN sensation4 weeks

    Sensation of numbness/tingling on 0-10 scale; minimum value 0 (no numbness/tingling); maximum value 10 (worst numbness/tingling)

  • Dual-task function4 weeks

    Ability to move and think at the same time as measured by time to complete the Timed-Up-and-Go (TUG) test with concurrent cognitive task (i.e., counting backward by some number while completing a defined movement task)