This study is looking into why women who have had preeclampsia (a serious blood pressure condition during pregnancy) might have a higher risk of heart problems later in life, especially how their bodies react to salt. Researchers are testing a drug called eplerenone to see how it affects blood vessel function in your skin when exposed to heat. They want to understand if problems with your blood vessels and a system in your body called the angiotensin system, which helps control blood pressure, are involved. To join, you must be a woman between 18 and 45 years old, and have given birth 12 weeks to 5 years ago, whether or not you had preeclampsia. The study aims to enroll 40 participants and is currently unclear about its recruitment status.

Study design

This is an interventional study planning to enroll 40 women. It compares the effects of eplerenone to a placebo (an inactive substance) on blood vessel function.

What's involved

You would undergo testing on Day 3 (while on a low-salt diet) and Day 10 (while on a low-salt diet with a high-salt supplement). You would also provide 24-hour urine samples on Day 2 and Day 9.

Compensation

Not stated in the trial record.

Follow-up

The primary endpoints are measured at Day 3 and Day 10, with urine samples collected on Day 2 and Day 9.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.