Understanding Colorectal Cancer Screening for Ages 45-54

This observational study aims to understand why some individuals aged 45-54 have not been screened for colorectal cancer (CRC). Researchers want to identify factors within health centers and from patients' perspectives that help or hinder screening. You might be eligible if you are 45-54 years old, a patient at the health center, and have no personal or family history of CRC, inflammatory bowel disease, or high-risk cancer syndrome. The study will measure how acceptable and practical different strategies are for encouraging screening. This will be assessed over a 12-month period, from planning to evaluation. The study plans to enroll 40 participants.

Study design
This is an observational study that aims to enroll 40 participants. It involves interviews with patients and surveys with health center staff.
What's involved
Participants will be asked to take part in a one-time interview, either online or in-person.
Compensation
Not stated in the trial record.
Follow-up
The study will assess outcomes over a total of 12 months.

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NCT06757192

CRC Screening in Unscreened Individuals 45-54

Recruiting
Not specifiedAges 45–54Observational
Massachusetts General Hospital
~40 participants
Updated 2025-11-13 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Measurement of acceptability and feasibility of implementation strategies
Measured over From planning to testing and evaluation and assessment of outcomes will be a total of 12 months
Colorectal Cancer Screening
1 sites across 1 states
Massachusetts1
  • Adjoa Anyane-Yeboa, MD, MPH · PRINCIPAL_INVESTIGATOR · Massachusetts General Hospital

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Eligibility criteria

Inclusion

Individuals aged 45-54
Individuals who are patients at the health center
Individuals that are willing and able to give verbal/written consent
Individuals ages 18+
Individuals working at the health center
Individuals that are involved in CRC screening processes at CSHC
Individuals that are willing and able to give verbal/written consent

Exclusion

Individuals with a personal history of CRC
Individuals with a family history of CRC
Individuals with a history of inflammatory bowel disease or high-risk cancer syndrome
  • Measurement of acceptability and feasibility of implementation strategiesFrom planning to testing and evaluation and assessment of outcomes will be a total of 12 months

    For our primary outcome, participants will be asked to rate the acceptability and feasibility of implementation strategies using a previously validated instrument, which the investigator previously used with CHC staff. This tool has demonstrated good internal consistency reliability (0.85 for acceptability and 0.89 for feasibility) and similarly good test-retest reliability (correlations: acceptability- 0.80; feasibility - 0.88) and validity in a known groups analysis. There are no cut off numbers for acceptability and feasibility as these are just means but higher scores reflect higher acceptability. However, our surveys will allow us to better understand our survey findings. Quantitative survey interviews will be collected after first and second cycle of testing. The surveys and interviews will be measured together as this is a mixed methods study.