Brain Stimulation for Hand Muscles in Chronic Stroke Patients
This study is looking at how a type of brain stimulation called rTMS (Repetitive Transcranial Magnetic Stimulation) might help improve hand movement in people who have had a stroke. Researchers want to see if different ways of giving rTMS, specifically FiTBS600, FiTBS2400, and DiTBS2400, can make the hand muscles more excitable. This could potentially help with motor recovery after a stroke. You might be able to join if you are at least 21 years old, had your first stroke at least 3 months ago, and have some weakness in one arm. The study will measure the effect of the stimulation on your hand muscles at the beginning and after the intervention.
- Study design
- This interventional study plans to enroll 26 participants to compare three different brain stimulation approaches.
- What's involved
- You would undergo brain stimulation using Transcranial Magnetic Stimulation and have your hand muscle excitability measured at baseline, and then again 45 minutes apart, before and after the intervention.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary endpoint is measured at Baseline, prior to and after intervention (Pre0 and Pre1; 45 minutes apart).
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
The Effect of Non-invasive Brain Stimulation rTMS on Hand Muscles in Chronic Stroke Patients.
At a glance
Conditions
NCT06765642
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
Duke University Medical Center
Durham, North Carolinastudy coordinator listed
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- Wayne Feng, MD · PRINCIPAL_INVESTIGATOR · Duke University
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- To determine whether there is overall stimulation effect among three stimulation paradigms (FiTBS600; FiTBS2400; DiTBS2400) on the ipsilesional corticospinal excitability of a hand muscle.Baseline, prior to and after intervention (Pre0 and Pre1; 45 minutes apart)
Each intervention session (total of 3) will consist of one format of iTBS stimulation. Before and after the intervention, single pulse TMS (spTMS) and motor sequence learning (MSL) will be used to assess the effect of the intervention on corticospinal excitability and motor performance.