Neocortical Microarchitecture of Executive Function in Parkinson's Disease
This study is looking at how a new high-resolution brain electrode, called the Neuropixels probe, can be used in the human brain. Researchers want to see if the Neuropixels probe can safely and effectively record from many brain cells during awake Deep Brain Stimulation (DBS) surgery. You might be able to join if you have Parkinson's disease, are between 45 and 85 years old, and need DBS surgery. The main goal is to measure how brain cells in a specific area (the middle frontal gyrus) represent task information. The study is currently unclear on its recruitment status and plans to enroll 15 participants.
- Study design
- This is an interventional study with a planned enrollment of 15 participants. It is not specified if it is randomized or blinded.
- What's involved
- A Neuropixels probe will be temporarily inserted into and removed from your brain during awake Deep Brain Stimulation (DBS) surgery.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary endpoint, measuring neural representations, is assessed at 20 minutes. It is not specified if there is follow-up after this time.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Neocortical Microarchitecture of Executive Function
At a glance
Conditions
NCT06778135
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
University of Colorado
Aurora, Coloradostudy coordinator listed
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- Measure the neural population representations of task parameters along, and within, the cortical layers.20 minutes