Knee Injections for Obese Patients With Knee Arthritis
This study is for obese patients (BMI of 30 or higher) who have knee arthritis and are considering a steroid injection. Researchers want to see if a lower dose of triamcinolone acetonide (a steroid) is just as effective as the standard dose for reducing pain and improving knee function. You would receive one of two types of knee injections: either a low dose of 20mg triamcinolone acetonide mixed with lidocaine (a numbing medicine), or a standard dose of 40mg triamcinolone acetonide also mixed with lidocaine. The study will measure your pain and knee function at the start, and then again at 4 weeks and 12 weeks after the injection. The current status of this study is unclear, and it plans to enroll 40 participants.
- Study design
- This is an interventional study comparing two different doses of a steroid injection. It plans to enroll 40 participants aged 55 to 85.
- What's involved
- You would receive a knee injection and have your pain and knee function measured at the start, 4 weeks, and 12 weeks.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for 12 weeks after the injection to assess pain and knee function.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Knee Injections for Obese Patients With Knee Arthritis
At a glance
Conditions
NCT06782529
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
Mayo Clinic in Florida
Jacksonville, Floridastudy coordinator listed
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- Jeffrey P Nadwodny, DO · PRINCIPAL_INVESTIGATOR · Mayo Clinic
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
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Exclusion
What this trial measures
- Numerical Pain Scale (NPS)Baseline, 4 weeks, 12 weeks
The Numerical Pain Scale (NPS) uses a 0-10 point rating system in which the patient selects the number that describes their current pain level, where "0" represents "no pain" and "10" represents "the worst pain imaginable"
- Knee Injury and Osteoarthritis Outcome score (KOOS)Baseline, 4 weeks, 12 weeks
The Knee Injury and Osteoarthritis Outcome is a commonly used questionnaire which focuses on how patients are affected by osteoarthritis symptoms in five areas: knee pain, stiffness, daily activity, sport and recreation, and quality of life. Results are scored 0-100. 0 = extreme problems, 100 = no problems.