The MAMA study is looking at how the pancreas changes during pregnancy in mothers and their babies, especially when the mother has diabetes. Previous research suggests pancreas size might be smaller in people with diabetes, and that it grows during pregnancy. This study uses magnetic resonance imaging (MRI) to measure these changes. You may be able to join if you are a pregnant woman, aged 18-54, less than 14 weeks pregnant with one baby, and plan to stay in the Austin area for one year after delivery. This is an observational study, meaning there are no interventions or treatments being tested. The study aims to understand how pancreas size relates to gestational diabetes (diabetes during pregnancy) and how a baby's pancreas develops.

Study design

This is an observational study that will follow up to 87 pregnant women and their babies. It is a prospective cohort study, meaning participants are followed over time.

What's involved

You would have study visits at approximately 15-18 weeks, 24-28 weeks, and 34-38 weeks of pregnancy, and again about one year after delivery. These visits include reporting height and weight, blood pressure checks, blood draws, a finger stick test (HbA1c), an oral glucose tolerance test (OGTT), an MRI scan, and continuous glucose monitoring (CGM).

Compensation

Not stated in the trial record.

Follow-up

Participants will be followed through pregnancy and for one year to one year and two months postpartum.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.