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Optimizing Support for Weight Loss Maintenance

This study aims to discover the best combination of strategies to help people keep weight off after losing it. Many people find it challenging to maintain weight loss, and this research will look at different approaches to see which ones work best without adding extra cost or burden. You might participate in activities like eating a reduced variety of foods (Reduced Food Variety), doing exercises at home to strengthen your muscles (Home-based Resistance Training), getting support from a friend or family member (Buddy Training and Support), or attending group workshops to learn new skills (Acceptance and Commitment Workshops). To join, you need to be over 18, have a BMI (Body Mass Index) over 30 kg/m2, and have internet access. The main goal is to see how much your weight changes over 12 months.

Study design
This interventional study plans to enroll 544 participants to test different behavioral strategies for weight loss maintenance.
What's involved
Participants assigned to Reduced Food Variety will choose specific meals and snacks monthly. Those in Home-based Resistance Training will exercise at home at least twice weekly. Buddy Training and Support involves identifying an eligible friend or family member. Acceptance and Commitment Workshops require attending six 1-hour group sessions over three months.
Compensation
Not stated in the trial record.
Follow-up
Your weight will be measured at 12 months after you start the study to see how well you've maintained your weight loss.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06785064

Optimizing an Extended Care Intervention to Promote Weight Loss Maintenance

Recruiting
NAAges 18+InterventionalTreatment
University of Alabama at Birmingham
~544 participants
Updated 2026-01-07 on ClinicalTrials.gov
What's tested:Reduced Food Variety (RFV)Home-based Resistance Training (HBRT)Buddy Training and Support (BTS)Acceptance and Commitment (ACT) Workshops

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in weight from time of randomization to 12 months
Measured over 12 months

Conditions

Obesity Prevention
Weight Change
Weight Loss
Weight Loss Maintenance

Explore related trials

Obesity

Where it's being run

1 sites across 1 states
Alabama1

Who to contact

Gareth Dutton
[email protected]
205-934-6876
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Age \>18 years
Body mass index (BMI) \>30 kg/m2
Has regular access to internet (to access Zoom videoconferencing platform)
If indicated during screening, willing to obtain medical clearance for exercise from their healthcare provider prior to enrollment

Exclusion

Current or recent (past 6 months) use of prescription weight loss medications
Weight loss \>10 pounds in past 6 months (other than postpartum)
Pregnancy or anticipating pregnancy
Another household member already participating in the study
Participation in another randomized research project
Uncontrolled hypertension (blood pressure \>160/100 mm Hg at screening)
Any of the following other medical conditions: myocardial infarction or cerebrovascular accident within the last 6 months; unstable angina within the past 6 months; NYHA Class III or IV congestive heart failure; type 1 diabetes; and chronic lung diseases that limit physical activity
Unable to identify potential buddy (i.e., adult friend or family member) for extended care intervention phase
Residing \>50 miles from the university (to attend assessment visits)
Planning to relocate out of the area in the next 18 months
Does not have internet access
Unwilling or unable to do any of the following: give informed consent; read/understand English; accept random assignment

What this trial measures

  • Change in weight from time of randomization to 12 months12 months

    The primary outcome of the study is the change in weight measurement from the time of randomization (after Phase 1 initial weight loss/the beginning of Phase 2) until the follow up visit 12 months later. Participants' body weight will be measured to the nearest 0.1 kg at each point using a calibrated electronic scale. The change between these two measures will be calculated.