Back to search results
NCT06786546

Type 1 Diabetes Autonomic and Vascular Function

Enrolling by Invitation
Not specifiedAges 18–70Observational
University of Texas at Austin
~72 participants
Updated 2025-09-12 on ClinicalTrials.gov

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Vascular Function
Measured over Blood flow will be measured at baseline for 5 min in supine position. During exercise, blood flow will be measured continuously for the 3 minutes of handgrip exercise.
+1 more outcome measured

Conditions

Type 1 Diabetes (Juvenile Onset)
Type 1 Diabetes
Diabetes, Autoimmune

Explore related trials

Type 1 Diabetes Mellitus

Where it's being run

1 sites across 1 states
Texas1

Who to contact

This trial hasn't published a contact. View it on ClinicalTrials.gov

Do you actually qualify for this trial?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

Type 1 diabetes or a Healthy control

Exclusion

BMI \> 40kg/m2
Cancer with current treatment
HIV
Smoker cigarettes
Are pregnant or breastfeeding

What this trial measures

  • Vascular FunctionBlood flow will be measured at baseline for 5 min in supine position. During exercise, blood flow will be measured continuously for the 3 minutes of handgrip exercise.

    Blood flow (ml/min) will be measured using Doppler ultrasound during steady-state dynamic exercise. Vascular conductance (ml/min/mmHg) will be calculated by dividing blood flow with blood pressure (mmHg). This measure will inform us about the vascular function in type 1 diabetic patients.

  • Autonomic FunctionBlood presure will be measured at baseline for 10 minutes and continuously during 2 minutes of isometric handgrip.

    Blood pressure (mmHg) will be measured using Finapres at baseline and during activation of exercise pressor reflex. The exercise reflex will be activated by performing 2 minutes of isometric handgrip exercise at 30% and 40% of the maximal grip strength. This will inform us about the autonomic function in type 1 diabetic patients.