Understanding Messages About Reduced Nicotine Cigarettes

This study is looking at how different messages about very low nicotine cigarettes (VLNCs) and policies for reduced nicotine affect adult smokers. Researchers want to see if these messages, combined with using VLNCs, can help people smoke fewer cigarettes. You would be exposed to messages about VLNCs through things like cigarette pack inserts, printed ads, and videos during weekly visits. Another group will receive VLNCs but see unrelated ads, like for bottled water. The study aims to find out if receiving these specific messages, along with VLNCs, leads to smoking fewer cigarettes per day compared to just using VLNCs without the messages. This study is currently unclear on its recruitment status and plans to enroll 1230 participants.

Study design
This is a randomized, open-label study involving 1230 participants. You would be assigned by chance to one of two groups: one receiving VLNCs with messages, and another receiving VLNCs without messages.
What's involved
You would participate in a 1-week baseline period followed by a 4-week study. This includes weekly visits where you would receive VLNCs and be exposed to messages.
Compensation
Not stated in the trial record.
Follow-up
Your cigarette use will be measured at Week 4 of the trial, after you've been randomly assigned to a group.

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NCT06787937

Communicating About Nicotine Reduction in Cigarettes

Recruiting
NAAges 21+InterventionalPrevention
Georgia State University
~1,230 participants
Updated 2025-10-29 on ClinicalTrials.gov
What's tested:VLNC messagesControl message

At a glance

Recruiting sites
2 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Cigarettes per day
Measured over Week 4 of the trial (post randomization)
Tobacco Products
Smoking Behavior
Cigarette Use
2 sites across 1 states
Georgia2

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Age 21+ years
Current smoker (self-report as having smoked 100 cigarettes in their lifetime and currently smoking on 27+ days out of past 30, expired breath carbon monoxide \[CO\] ≥6ppm to assess regular smoking)
Can speak, read, and write in English
Available for period of study
Willing to try novel research cigarettes

Exclusion

Pregnancy or lactation
Member of the same household as a study subject
Unwilling to use research cigarettes as part of the trial
  • Cigarettes per dayWeek 4 of the trial (post randomization)

    Number of cigarettes smoked per day (study and non-study cigarettes). * Averaged number of cigarettes smoked based on 7 days' daily logs submitted through text-based survey during the last week of the trial. * Response: integer indicating number per day.