External Trigeminal Nerve Stimulation for Migraine During Pregnancy

This online registry is studying how safe and effective external trigeminal nerve stimulation (e-TNS), marketed as CEFALY, is for treating migraines in pregnant women. CEFALY is a non-invasive, non-drug device approved by the FDA for migraine treatment. You can join if you are a woman between 18 and 44 years old, pregnant with one baby, and have access to email or text. You don't need to use CEFALY or any other migraine treatment to participate. The study will look at miscarriage rates and how mothers bond with their babies after birth. The goal is to see if CEFALY is a good option for migraines during and after pregnancy. The study is currently unclear on its recruitment status and aims to enroll 550 participants.

Study design
This is an observational study, meaning researchers will collect information without making changes to your treatment. It aims to enroll 550 pregnant women.
What's involved
You will complete online surveys for screening, enrollment, and data collection. There are no clinic or research visits.
Compensation
Not stated in the trial record.
Follow-up
Your progress will be tracked through study completion, which is an average of 2 years.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06788977

External Trigeminal Nerve Stimulation for Migraine Treatment in Pregnancy

Recruiting
Not specifiedAges 18–44Observational
Cefaly Technology
~550 participants
Updated 2026-04-15 on ClinicalTrials.gov
What's tested:external Trigeminal Nerve Stimulation

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Rate of miscarriage per trimester
Measured over through study completion average 2 years
+1 more outcome measured
Pregnancy
Migraine
Headache
Postpartum
Depression
Anxiety
1 sites across 1 states
Connecticut1
  • Deena Kuruvilla, MD · PRINCIPAL_INVESTIGATOR

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  • Rate of miscarriage per trimesterthrough study completion average 2 years
  • Postpartum Bonding according to the Maternal-to-Infant Bonding Scalethrough study completion average 2 years

    The "Maternal-to-Infant Bonding Scale" is a scale which measures the mother's feelings regarding her child within the first few weeks after birth. The score of teh scale can range from 0 which denotes favorable or good outcome whereas the maximum score is 24 indicating a poor outcome.