Mindfulness for Cognition in Early-stage Alzheimer's Disease
This study is exploring if a mindfulness meditation program, called the Mindfulness Intervention (an adapted form of Mindfulness-based stress reduction or MBSR training), can help improve thinking, memory, and daily function in older adults. This includes people with Mild Cognitive Impairment (MCI), MCI due to Alzheimer's Disease, those with a history of Traumatic Brain Injury (TBI), and healthy older adults. Researchers want to see how mindfulness affects your brain and overall quality of life. You would either participate in a 10-week virtual mindfulness class or be on a waitlist for the class before eventually taking it. The study aims to enroll 100 participants.
- Study design
- This interventional study plans to enroll 100 participants. It compares a group receiving mindfulness training to a group that waits before receiving the training.
- What's involved
- You would participate in a 10-week virtual mindfulness class. Your thinking, memory, and brain activity would be measured before and after the intervention.
- Compensation
- Not stated in the trial record.
- Follow-up
- Measurements are taken from before the intervention to 10 weeks after the intervention.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Mindfulness for Cognition in Early-stage Alzheimer's Disease
At a glance
Conditions
Where it's being run
1 sites across 1 statesWho to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Neuropsychological testsFrom before the intervention (baseline) to after the intervention (post-intervention 10 weeks)
Paper-and-pencil tests measuring attention, processing speed, and memory.
- Performance on computerized tasksFrom before the intervention (baseline) to after the intervention (post-intervention 10 weeks)
Reaction time and accuracy on computer tasks measuring attention and memory
- Resting state and event-related electrophysiologyFrom before the intervention (baseline) to after the intervention (post-intervention 10 weeks)
Electrophysiology measured while at rest and time-locked to performance on a computerized task measuring attention and memory
- Brain function and structureFrom before the intervention (baseline) to after the intervention (post-intervention 10 weeks))
Blood-oxygen-level-dependent (BOLD) for functional magnetic resonance imaging. Voxel-based morphometry (VBM) and diffusion tensor imaging (DTI) for structural magnetic resonance imaging.
- Survey outcomesFrom before the intervention (baseline) to after the intervention (post-intervention 10 weeks))
Surveys measuring mood, social isolation, sleep, and quality of life