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ICG Fluorescence Imaging for Open Fractures and Infections

This study is looking at whether a special imaging system using indocyanine green (ICG) fluorescence can help surgeons understand bone health and blood flow in patients with severe open fractures (where the bone breaks through the skin) or bone infections. ICG is an FDA-approved dye given through a vein, and the imaging system is also FDA-approved. The goal is to see if this information helps surgeons choose the best treatment and predict potential problems like the need for more surgery or infections. You might be able to join if you are 18 or older and have an open extremity fracture or a fracture-related infection requiring surgery. Researchers will measure how many participants need another surgery or get an infection within 12 months.

Study design
This is an observational study, meaning researchers will watch and collect information without assigning specific treatments. It plans to include 10 participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 12 months to track reoperations and infections.

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NCT06793644

Study of ICG Fluorescence Imaging in Open Fracture and Infection Patients

Recruiting
Not specifiedAges 18+Observational
Dartmouth-Hitchcock Medical Center
~10 participants
Updated 2026-03-19 on ClinicalTrials.gov
What's tested:Immunofluorescence Imaging

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Number of participants who undergo an unplanned fracture-related reoperation
Measured over 12 Months
+1 more outcome measured

Conditions

Fractures, Bone
Trauma Injury

Explore related trials

FractureFracture Related Infection

Where it's being run

1 sites across 1 states
New Hampshire1

Study leadership

  • Ida L Gitajn, MD · PRINCIPAL_INVESTIGATOR · Dartmouth-Hitchcock Medical Center

Who to contact

Jon Mikael Anderson
[email protected]
603-653-3306
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Patients 18 years of age or older.
Open extremity fracture, planning for management with external fixation, internal fixation or joint fusion.
Fracture Related Infection, planning for management with debridement and possible removal of hardware.
Will have all planned fracture care surgeries performed by a participating surgeon or delegate.
Provision of informed consent.

Exclusion

Inability of patient to provide informed consent
Fracture of the hand.
Iodine allergy.
Burns at the fracture site.

What this trial measures

  • Number of participants who undergo an unplanned fracture-related reoperation12 Months

    All unplanned reoperations will be documented using a specific case report form

  • Number of participants who experience a post-procedure surgical site infection12 Months

    Post-procedure surgical site infection using Centers for Disease Control criteria will be documented at each follow-up