Study of a Postbiotic for Oxidative Stress and Exercise Performance

This study is looking at how a dietary supplement called Postbiotic Active Lifestyle Blend affects healthy adults who exercise. Researchers want to see if this blend can reduce oxidative stress (damage to cells from exercise) and improve exercise performance. You would take either the Postbiotic Active Lifestyle Blend or a placebo (an inactive capsule that looks the same) for 8 weeks. The main goal is to see changes in a marker of oxidative stress called malondialdehyde in your blood before and after exercise. This study is for healthy men and women between 18 and 45 years old. The current recruitment status is unclear.

Study design
This is a randomized, double-blind study, meaning you would be randomly assigned to receive either the active supplement or a placebo, and neither you nor the researchers would know which you are receiving. About 80 healthy adults are planned to participate.
What's involved
You would participate in an 8-week intervention period, with assessments at the beginning, middle, and end. These assessments include blood draws, VO2 peak testing, and exercise performance tests. You would also keep a daily diary.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint is measured after 8 weeks of supplementation.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06795425

A Randomized, Double-Blind Study to Assess the Effect of a Postbiotic on Oxidative Stress and Exercise Performance

Not Yet Recruiting
NAAges 18–45InterventionalTreatment
Lindenwood University
~80 participants
Updated 2025-01-28 on ClinicalTrials.gov
What's tested:Postbiotic Active Lifestyle BlendPlacebo

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change from Baseline in Serum Malondialdehyde Concentrations 30 Minutes Before and 30 Minutes After Exercise Completion After 0 and 8 Weeks of Supplementation
Measured over 30 minutes before and 30 minutes after exercise completion at baseline (0 weeks) and after 8 weeks of supplementation.
Oxidative Stress
Healthy
Exercise-induced Muscle Damage
Exercise-induced Muscle Soreness
Immune Function
Gut Health
Microbiome Analysis
Exercise Performance
Exercise Metabolism
1 sites across 1 states
Missouri1
  • Chad M Kerksick, PhD · PRINCIPAL_INVESTIGATOR · Lindenwood University

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  • Change from Baseline in Serum Malondialdehyde Concentrations 30 Minutes Before and 30 Minutes After Exercise Completion After 0 and 8 Weeks of Supplementation30 minutes before and 30 minutes after exercise completion at baseline (0 weeks) and after 8 weeks of supplementation.

    Serum malondialdehyde (MDA) concentration will be measured to assess the effect of the postbiotic blend on lipid peroxidation and oxidative stress. Higher MDA levels indicate increased oxidative stress.