Acceptance and Commitment Therapy for Chronic Migraine

This study is testing if a behavioral therapy called Acceptance and Commitment Therapy (ACT) can help adults with chronic migraine feel less disabled by their headaches. Researchers want to see if adding ACT to your usual migraine treatment improves your daily functioning and activity, as well as headache frequency and pain. You would be eligible if you are between 18 and 65 years old, have chronic migraine, and are a patient at the Graham Headache Center. The study plans to enroll 40 participants. The main way they will measure success is by looking at changes in your Headache Disability Index scores after 3 months.

Study design
This is an interventional study planning to enroll 40 participants. It compares adding Acceptance and Commitment Therapy (ACT) to usual headache treatment versus usual headache treatment alone.
What's involved
If selected for ACT, you would take 8 classes to learn ACT and then practice it at home, in addition to your regular headache treatment.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint is measured at 3 months, suggesting follow-up for at least that duration.

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NCT06795867

Acceptance and Commitment Therapy to Improve Disability in Chronic Migraine

Recruiting
NAAges 18–65InterventionalTreatment
Brigham and Women's Hospital
~40 participants
Updated 2025-10-31 on ClinicalTrials.gov
What's tested:acceptance and commitment therapy

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in Headache Disability Index
Measured over 3 months
Chronic Migraine
1 sites across 1 states
Massachusetts1

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Willingness and ability to engage in the consent process
Willingness to participate in the study, despite randomization outcome
Availability for the duration of the study
Diagnosis of chronic migraine followed at the Graham Headache Center
Access to the necessary resources for participating in a technology-based intervention

Exclusion

Known major depression or other psychiatric condition
Non-English speaking
Secondary headache diagnosis
Psychotherapy in the prior 18 months
Any reason the provider feels would limit participant ability to learn or practice ACT
Any previous experience with mindfulness or meditation approaches
  • Change in Headache Disability Index3 months

    Change in Headache Disability Index from baseline to 3 months. Scores at 3 months minus scores at baseline.