Observational Study of Stellate Ganglion Block on Retinal Microcirculation

This observational study is looking at how a stellate ganglion nerve block affects the tiny blood vessels in your retina (the back of your eye). Researchers want to see if this nerve block, which is sometimes used for conditions like complex regional pain syndrome, can improve blood flow in the eye. They believe that too much activity in a part of the nervous system (the sympathetic nervous system) after brain injuries like a stroke or bleeding in the brain might cause problems, including narrowing of blood vessels. You might be able to join if you are 18 or older, are receiving a stellate ganglion nerve block for a medical reason, and can sit up for an eye scan. The main goal is to measure changes in blood vessel density and blood flow one day after the nerve block. The current status of this study is unclear.

Study design
This is an observational study planning to include 50 participants. It is not a randomized trial.
What's involved
You would have an OCTA Scan (a special eye scan) before and after receiving the stellate ganglion nerve block.
Compensation
Not stated in the trial record.
Follow-up
Vascular and perfusion density will be measured one day after the intervention.

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NCT06797752

Effect of the Stellate Ganglion Block on the Retinal Microcirculation

Recruiting
Not specifiedAges 18+Observational
University of Texas Southwestern Medical Center
~50 participants
Updated 2025-11-19 on ClinicalTrials.gov
What's tested:OCTA Scan

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Vascular and Perfusion Density
Measured over One day
OCTA
Severe Brain Injury
Subarachnoid Hemorrhage
Intracerebral Hemorrhage
1 sites across 1 states
Texas1
  • Noah Jouett, DO, PhD · PRINCIPAL_INVESTIGATOR · University of Texas Southwestern Medical Center

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Eligibility criteria

Inclusion

Age 18 years or older
Patients receiving the stellate ganglion nerve block for an approved indication, e.g. complex regional pain syndrome

Exclusion

Pregnancy
Non-English speaking
Temporary or permanent physical limitation that renders the patient unable to sit up and look inside OCTA device
  • Vascular and Perfusion DensityOne day

    Quantitative measure of retinal microperfusion